I have severe mood swings, I have agitated depression, when i have "a manic freakout" which usually lasts a couple of minutes and then comes the guilt for having the freakout. My question is I have tried many medications for this throughout the years along with counseling. Zoloft, celexa, effexor, trazadone, wellbutrin(allergic) prozac(allergic) cymbalta and pristique with lexapro, they helped a little with the depression but not the horrible mood swings or episodes of freaking out. i seriously lose it momentarily and then i feel absolutely horrible about myself after. what else is there to try for this behavior. I do have xanax prn but it's usually too late by then.