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What's best to try next

So I'm currently taking 75mg venlafaxine and 15mg mirtazapine the mirtazapine is great doing its job for the night time anxiety it's more than enough to calm me and help me sleep the night but my concern is the venlafaxine it's causing me stomach upset and feelings of low mood iv been taking this combo since beginning of December whilst some what it has levelled me out to the state I was currently in I don't feel as tho the venlafaxine is helping anymore as Iv been on it before and known when it was not doing way it is supposed to my question really is why have people switched over to from this with good results
Thank you
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