Depression Community
10.6k Members
1354136 tn?1331878917

Zoloft 50mg and feeling hungry

Hello board. I have been on zoloft 50mgs for a week and a half. I don't notice any change in my mood. In fact I feel more tired. Any ways I have read so much on zoloft and weight gain. However has anyone experienced a feeling fuller faster feeling with this med and a sense of hunger rather quickly after eating?

Just wondering since that is what I'm going through. I get fuller faster on smaller amounts of food but then about an hour later it's like I haven't eaten all day. Naturally I don't eat each time that hunger feeling arises just wondering if anyone else noticed those side effects.
3 Responses
1042487 tn?1275283499
Yes, changes in the monoamines or reuptake pumps (SSRI like Zoloft) can have significant impacts on your metabolism and promote a ''being hungry'' feeling.

I must let you know that you probably wont get any changes in your mood until you have been 2-4 weeks on the drug. This is due to the adaptation in your brain to the reuptake inhibition caused by Zoloft.

Almost any drugs that have an impact on your serotonin levels (5-HT* receptors) will usually lead to metabolism changes. A good way to counter this effect is to go for a SNRI or add a drug like Wellbutrin to get a dopamine and norepinephrine reuptake inhibition which would suggest reduced appetite and increased energy which would prone a faster metabolism.

I would try the Zoloft until the therapeutic lag is gone then I would weight the income vs the outcome. Do you want to add another medication to Zoloft which, by the way, is not supposed to have significant weight gains from using the drug but everyone is different or not.

Some people have to try several medications before they find one that suits them.

1354136 tn?1331878917
Hey. Thank you for the info. I'm looking to just give this zoloft a try for now. I had just read all these weight gain horror stories about zoloft and now that I have taken it I notice I get a hunger feeling more often. However I still keep my meals in check. I was just thinking if this makes you feel hungry more often maybe people are more prone to eat more and that could be a cause if the weight gain.

Just an observation. I didn't think just taking a med would increase your weight wouldn't it be what you put on your mouth?
1042487 tn?1275283499
Zoloft on it's own is not supposed to cause weight gain. The weight gains observed are mostly due to increased calories intake, modification of lifestyle habits.

Have an Answer?
Top Mood Disorders Answerers
Avatar universal
Arlington, VA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
15 signs that it’s more than just the blues
Discover the common symptoms of and treatment options for depression.
We've got five strategies to foster happiness in your everyday life.
Don’t let the winter chill send your smile into deep hibernation. Try these 10 mood-boosting tips to get your happy back
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.