Depression Community
10.6k Members
Avatar universal

Zoloft dosage too high?

I'm currently taking zoloft at a dose of 200mg daily, in the morning. My doctor's instructions were to go all the way up to the maximum dose of zoloft because he believes that my combination of depression, anxiety, PTSD and bulimia might simply be treatment resistant. I've been on zoloft twice before, but never at a dose any higher than 150mg.

I've been on the 200mg dose of zoloft for five weeks now, and though I had initial side effects they did go away. However, all of the physical side effects such as dry mouth, excessive sweating, nausea, diarrhoea, feeling uncomfortable in my own skin, and crying at the drop of a hat have all come back with a vengance. Typically they ease up by early afternoon, but these side effects are making it very hard for me to function in the morning.

I really don't know what to do because I can't stand feeling like this, but the medication is helping even out my mood to some extent. Should I persist with the zoloft at this dosage and see if the side effects go away or ask my doctor to taper down?

Has anyone experienced anything similar with SSRIs? How did you deal with it?
2 Responses
480448 tn?1426952138
You're five weeks into the dosage change, therefore any side effects you had as a result of stepping up should be mostly resolved.  I think it would be wise to talk to your doctor.  Is it possible that some of your symptoms could be related to anxiety and/or depression versus side effects?  That's a pretty common problem, people are afraid of the meds, or increasing the meds and cause anxiety which one then relates to side effects.

As to whether your dose is too "high"?  That's an individual thing,  I was on Zoloft years ago, and my final dose was 200mg.  It worked great, minus a few of those initial side effects.  It's not "too high" as far as prescribing standards, no.

Did you go up the 200mg dose from 150mg?

Hopefully we can help you sort through this.  Definitely keep in touch with your doctor about what's going on.
Avatar universal
Thats a good question, do you keep going even if the side effects are horrible?

I am a 22 year old college student who takes zoloft. I love my life and my friends and family but yes I take zoloft. At first, it was a lifesaver and i believe it is a GREAT medicine. However, I have been sweating verrrryyyyy badly lately. It is at the point where I am so embarressed to go out...

My boyfriend has noticed.. So have my friends. I work hours on my hair but what is the point. it ends up turning into a pool of water.

what sux is that I live now in Missouri...so yes it is hot. BUT WHY AREN'T ANY OTHER GIRLS DRIPPING IN SWEAT

I hate that I have to complain about this....its sooooo random!!

But I am. But guess what to the people reading this...you aren't alone.   This happens. Oh Well...we still look hot as hell going out!

Have an Answer?
Top Mood Disorders Answerers
Avatar universal
Arlington, VA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
15 signs that it’s more than just the blues
Discover the common symptoms of and treatment options for depression.
We've got five strategies to foster happiness in your everyday life.
Don’t let the winter chill send your smile into deep hibernation. Try these 10 mood-boosting tips to get your happy back
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.