These data suggest that patients with aquagenic urticaria react to a water-soluble antigen in the epidermal horny layer that diffuses into the dermis to cause histamine release from sensitized dermal mast cells.
Journal of the American Academy of Dermatology
Volume 15, Issue 4, Part 1, October 1986, Pages 623–627
Thus it looks to me that your child indeed has a aquagenic urticaria from the fact that she responds to water of any temperature with whealing and not just itching.(aquagenic pruritus).
I forgot to include that these hives are only on her torso (back and front) and her shoulders and neck and sometimes under her chin.
The present concept is that any type of water at any temperature carries an unknown allergen present in the skin across the skin barrier, causing the wheals.This can coexist with other forms of physical urticaria,though rarely.
In fact injecting water into dermis does not produce the rash! That means while water permeates the skin barrier, the allergen gets mixed.ok?
Thank you for responding. Are you a physician? Also, do you know if the water temperature can change the amount of wheals? If hot, there are more wheals, if cold then there are less wheals.
Also, can the amount of wheals change based on different types of water? (Tap, sea, etc...) THANK YOU!
As I mentioned to you earlier the very diagnosis of aquagenic urticaria, by definition hinges on the finding of urticaria produced byANY water at ANY temperature.The whealing is not dependent on other factors.
If temperature varies and that is the factor it it would be more of a cholinergic urticaria.
While I am indeed a physician, here my capacity is that of a community member!
Also Cyproheptidine (periactin) is very effective here but do consult your doc. ok?
Absolutely calling a Dermatologist in the morning. I appreciate your help.
You were right. :D Thank you!
do you have black mold in your home? i was reading about black mold and your daughters symptoms seem that the same, almost exact same as those of people suffering from exposure from black mold and the information i was reading about said that there are MANY misdiagnosed diseases that black mold ingestion can actually be the cause of or trigger the onset of diseases...i dont know...i just thought i would share information i recently learned.