I am a 30 yr old insulin dependent diabetic. I grew up not paying attention to it and was frequently in the hospital, not eating right, DKA, etc. I always had high blood sugars until I began taking care of it in my 20's. I had angular cheilitis at a young age and didn't do anything about it except opening my mouth which made it feel better temporarily. Eventually after 10 yrs, I decided to do something about it and saw a doctor that prescribed me mycolog. It relieved the problem about 50%. Through the years I had tried numerous antifungal creams, but if I didn't see an improvement within 48 hrs, I would become discouraged and stopped treating it. The corners of my mouth are red with fissures on a constant basis and nothing, I mean NOTHING has helped at all. I have been suffering years and all I need is help with making this go away....for good! I have tried everything from mycolog to miconazole, hydrocortisone, clotrimazole, ketoconazole, etc. Is it hopeless? Do I need to get a culture to find out the exact thing that I cannot heal from? PLEASE help me...this makes me very frustrated! All I want is to be looked at without people touching the corners of their mouth when they talk to me. Just make this disappear! PLEASE!