The half life of IV antibiotics is fairly short which means it should wash out of your system relatively quickly. Rash is a common side effect for antibiotics for sure. Since it was a pre op IV antibiotic you are on, I assume you are no longer on antibiotics or did they give you one post operatively as well? You've narrowed this down to the pre op meds? A rash is usually considered an allergic reaction to the antibiotic. Stopping it is generally recommended but I would certainly check in with the prescribing doctor prior to doing that. In fact, that would be what I'd do now if you still have this rash. The doctor who performed the surgery should have an on call number to call and let them know. Was it an outpatient surgery? I'm just wondering when the rash appeared. Doctors can give you medicine to alleviate the rash if it is an allergic reaction. Anyway, sorry this happened!
Do you know what antibiotic was given to you? What symptoms are you having?