MedHelp.org will cease operations on May 31, 2024. It has been our pleasure to join you on your health journey for the past 30 years. For more info, click here.
Avatar universal

Hyperpigmentation/irritation after using Epiduo

Three and a half years ago i used Epiduo on my forehead, temples and nose. I did expose to 45 mins of morning sun without spf.

My skin turned red, then brown. The inflamation/irritation still persists. I can feel the skin thicker (like inflamed skin feels like) when i raise my eyebrows. The area looks brown. It becomes more red when i touch it.

Texture on those areas is different and the skin is a little raised.

I've tried azelaic acid 20%, ascorbic acid 20%, kojic acid, glycolic acid, salicilyc acid, tranexamic acid, adapalene, tazarotene 0,1%, hidroquinone which made it worse, mercury bleaching cream, BBL, laser peel (resufacing), flucinolon.

I think flucinolon worked best, but i can't use it long term on my face. When i use it, the inflamation and hyperpigmentation subside, but effects are immediatly reverted if i stop using it.
1 Responses
Sort by: Helpful Oldest Newest
973741 tn?1342342773
Gosh, that's hard. I have hyper pigmentation on my face. I had a terrible bout of it in my twenties due to a hormonal imbalance. My skin did feel the same though and not thicker. Sun made it worse. I used Renova at that time and it helped a lot. So expensive though. I haven't had a script for it in many years but think about it often as I've got some pigmenting going on again. It's in less conspicuous places and saw a dermatologist about it who was not concerned. I didn't get the script to renova as I got nervous and forgot to ask for it. sigh.

Laser resurfacing didn't help?

When you read about epiduo, it says it HELPS hyper pigmentation. Sigh, but everyone is different. I do think the cream you say works is short term use only  

Have you heard of this? https://jddonline.com/articles/post-inflammatory-hyperpigmentation-a-review-of-treatment-strategies-S1545961620P0763X  Supposedly, this reduces appearance of hyper pigmentation in 2/3 of the people who used it in clinical trials.
Helpful - 0

You are reading content posted in the Dermatology Community

Top Dermatology Answerers
Learn About Top Answerers
Popular Resources
Learn to identify and prevent bites from summer’s most common pests.
Doctors argue for legislation to curb this dangerous teen trend in the latest Missouri Medicine report.
10 ways to keep your skin healthy all winter long
How to get rid of lumpy fat on your arms, hips, thighs and bottom
Diet “do’s” and “don’ts” for healthy, radiant skin.
Images of rashes caused by common skin conditions