I can understand your worries regarding this sore area which is not healing. I looked at the picture you uploaded on the community forum and on looking closely there are smaller lesions around the big one. Also, you appear to be having faint small lesions on the skin around hair follicles or they may be a normal finding in your case.
Since the round itchy sore patch is present on the leg, it could be an insect bite. Scratching could have increased the soreness and extent of spread of inflammation beyond the sting. Another possibility is a contact dermatitis. This is an allergic reaction due to something that came in contact with your skin such as a plant, a chemical or some thing else. So, go over your routine for last 48 hours and see if you can identify a source of allergy or remember an insect biting you. This can be treated with anti-allergic and anti-inflammatory pills and ointments. Also, since you have been having hives for last few days, you may be having allergy to some food item or something you came in touch with and this sore itchy area may just be a larger patch of hive. It may help to make a list of things you are eating and hives as they are appearing to find out if there is a link.
Other than this it can be nummular eczema or psoriasis. Such sore red patches can also be due to blood clots/deep vein thrombosis. Hence, this aspect should be considered if you have pain and cramps in calf when you walk or run.
Birth control pills (in females) and blood thinners too can cause a sore bruise. However, usually they are more than one. Similarly multiple painful red patches can be due to thyroid medications, lupus, discoid eczema etc. Rarely, a persisting red sore patch can be due to skin cancer.
It could be a fungal infection if anti-fungal ointments are helping, but looks less like a fungal skin infection. It could be Herald patch (less likely based on the image), which is a solitary, oval, red colored patch which appears on the chest or abdomen (may be they came earlier or they may not have come and lesion first started on leg). After 1-2 weeks of this solitary patch, large patches of pink or red, flaky, oval-shaped rash appear on the torso. The rash may be accompanied by low-grade headache, fever, nausea and fatigue and itching. Treatment is by topical and oral steroids. Water, sweat, and soap may cause irritation and should be avoided. Topical zinc oxide and calamine lotion are useful for pruritus if it occurs.
To me it looks more like an allergic dermatitis, however, please discuss with your doctor for a confirmed diagnosis and management. Hope you get well soon! Good Luck and take care!
It is difficult for me to think about what I had eaten for the last 48 hours in relation to this sore because it has been on my leg for 7 days now without healing. Like I said last weekend which is seven days ago. Anyways so you think this is an allergic reaction? Just to be clear. I live in Thailand so I would like to try one thing before going into the doctor. BTW it does not itch. It is just red and dry. Sometimes fading and sometimes a little red.
I absolutely have no pain in my leg as well so what would you suggest as a possible treatment before seeing the doctor?
If the lesion does not itch or causes pain, it could be a herald patch of pityriasis rosea. A red non painful patch can be a bruise. Deficiency of Vitamin B12, folic acid, or Vit K could be the cause. They could also be fragile spider veins. It can be due to deep vein thrombosis (however usually there is pain on pressing). It can be a hemangioma, heat rash or allergy. However, since you had lot of dry skin over it which you peeled off—it is more likely to be eczema, dermatitis (allergic or non-allergic) or psoriasis.
Will it heal on its own do you think?
I am 43 so some of these suggestions of yours I read about and usually affect females and people over 50. I am male and 43
I am not happy with this service. I said In my original question it did not hurt or itch and you went ahead and commented on my round itchy sore. Please transfer my question to Bhupinder Kaur, MD