Neurontin/Lyrica angioedema?

[sk8flo]

I now know that the drugs Neurontin and Lyrica can produce angioedema, but how can I be sure it is not from something else.  First with Neurontin 300 mg. HS on 5th morning my lower lip looked slightly swollen and white underneath as if I had had Botox.  A month later I was put on Lyrica 50 mg. HS which was really beginning to resolve the C7 radicultitis when I awoke on day 13 with both lips slightly swollen, thick, same whiteness below lower lip.  That was yesterday morning.  No problems with tongue, throat, etc. My lips are still the same today.  My eyes feel slightly irritated, but no other symptoms except slightly swollen abdomen.  I'm 61, 5'5", 108 lbs.

Is this angioedema?  What is in these drugs that is the causative agent?  The only other drug that has ever given me a problem was a sulfa NSAID and 3rd dose gave me hives all over my abdomen.

Should I follow up with a dermatologist about this?

[BhumikaMD]

Hi,

Glad the post was some help to you. I n medicine there is a considerable overlap in terns of symptoms, diagnosis and treatment - so it is alright for you or anyone to be a little confused. You could post your question at multiple sites , without any inhibitions whatsoever.

I am posting the reply again - just for the benefit of someone who has similar complaints as yours.

Have you taken oral antiallergic or antihistamine medications for your symptoms? Take loratadine or cetrizine , it will help the lip swelling to subside.

It would be nice of you to write back and keep us posted about how you are doing and if you have any other doubts.

Also let us know about how your appointment goes.

Regards.

[sk8flo]

Thank you for your response.  I saw your answer in the Allergey Forum.  I double posted as I was not sure whether this was appropriate for an allergist or dermatologist.  Some eMedicine articles talked about seeing a dermatologist.  I hope I have not offended you, which ever speciality you practice.  Thank you again.

[BhumikaMD]

Hi,

You should consult an allergy specialist - especially since you have had allergic reactions in the past and are allergic to specific drugs/ medications.

Have you taken oral antiallergic or antihistamine medications for your symptoms? Take loratadine or cetrizine , it will help the lip swelling to subside.

You could talk to your doctor/ allergy specialist about the symptoms that you are having and after a clinical examination he/she would be able to tell you whether this is an allergic reaction to the drugs.

Let us know about any other doubts that you have and about how you are doing.

Post us about what the doctor advises.

Regards.