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Penis Edema

I am suffering on and off from severe painful angioedema of distal half of the penis area that has been happening for almost a year now and nothing seems to help me.
Angioedema happens by itself and sometime triggered from friction from just walking or running and starts with tingly sensation and then followed by edema and painful urethra with and with out urination.
My urine, blood count, STD all came back negative.
I have tried every possible thing I could to get the relief.
Taken Antihistamine and steroid no help.
I have tried to change soup, lotion, detergent and body wash.
Even changed and bought new underwears but painful edema still comes back.
I saw Dermatologist and urologist and seeing an allergist as well and things are not going anywhere.
I am depressed and stressed out not knowing what future holds for me with this situation.
is there someone going through same issue?
any suggestions or advice will be really appreciated.

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