I've had this problem for 4 years now, And no one can tell me why/what is wrong. It starts off with a itchy red patch on the palm of my left hand, And never goes anywhere else, just that one area. Then they turn into a cluster of tiny bumps or sometimes a few larger bumps that itch terribly. It has never spread to anywhere else on my body, or to anyone else. It first happened when i went to Texas and drove home, I thought it was blisters from driving so much, But then it came back over and over again. If it is the bigger bumps they turn into water blisters, and if popped water/blood come out of them, then they dry up and go away. What in the heck is this? I've tried cortisone cream but does not help, And why is it only on that small part of my body???