Hello -- I have a spot that has developed on my lower lip, near the corner of my mouth. It is toward the lower edge but not at the vermillion border. It started as a little spot, became sore, than scabbed over -- resembling much like a pimple with a whitehead. No multiple spots, thick scab, etc. It improved in 3-5 days but didn't quite disappear completely (looking like a small pinhead red spot but no soreness or pain). That was 10 days ago, and now it seems to be becoming sore again (especially after brushing) and red around it. I have had a similar spot on the opposite side that healed in 3-4 days. I have had multiple blood tests for Herpes, all of which have been negative. I have had little spots develop inside my mouth periodically, which my primary care practitioner has told me is likely stress related, and I've changed toothpastes, which seems to have helped those. Still concerned this could be herpes, although symptoms are somewhat different. And I've had 3 negative blood tests over the past year -- the last one being when the sore was healing a few days ago. Could it be some sort of pimple? I've tried different lip balms, but don't seem to be any difference. I've wondered about the accuracy of the blood tests, but I've been assured they are very accurate, especially if it has been many weeks since a person was infected. I have some fordyce spots, and it is definitely not those. Putting alcohol on it seems to make it a little more sore and swell for a bit, but that's probably because the lip tissue is sensitive.