For 10 months I have had recurring blisters on 2 toes, the great toe and the second toe of my left foot. At the onset I had severe itching of my second toe and the top of the foot. This was followed by tiny blisters, burning, and throbbing. One blister grew to the size of a half garbanzo bean, remained about 10 days, drained, and healed. After the blister was full grown the itching subsided. This process has repeated itself 12 times to date. Blisters sometimes engulf the whole toe. The last one on my big toe was the size of a large, fat lima bean. The blisters are usually on the inside, near the end of the toe rather than in the crease, and sometimes grow around to the bottom.
Also at the onset, I had stayed overnight 10 times in a hospital with a friend recovering from surgery. I noticed that I was having the random hive(s) here and there anyplace on my body. I also was experiencing swollen lumps on my lips. I am prone to cold sores, and thought these were cold sores, but they would disappear and not be as tender as herpes. These other skin problems have not been constant, though I still have 4 or 5 hives on my body occasionally. I was wearing sandals the entire time I was "staying" in the hospital. Stressed.
I have been to podiatrists, a dermatologist, infectious disease specialists, a rheumatologist, and my family doctor. I have followed the instructions anyone has given me. The dermatologist said it was herpes and I took the meds. I became ill shortly afterwards while in Thailand, erupted a new blister, and had BP 220/140. A Thai doc suggested I be tested for SLE. I was. Very low positive, which the rheumatologist said was not positive, and that I don't have lupus. The IDS did cultures (fluid and tissue) and all results were negative, including herpes. I now have an appointment with another dermatologist in 5 months. Will I have a blister to show him?
In the meantime, these lesions erupt about every 2 - 6 weeks. When they are erupting they are very distracting. It takes 3 - 4 days for the itching, burning, throbbing, and occasional sharp pain to subside. The only relief I have found is applying ice directly to the inflammed, swollen area. When the blister has erupted and the pain has subsided, there is sometimes another area that stays inflammed, though it doesn't become a problem unless it is rubbed, or certainly, if it is scratched. There are also times when one or both of the toes become "ready" to blister, but don't. They just give me fits with the itching, which I try to ignore.
The blisters and swelling sometimes prevent me from putting on a shoe. By the way, I wear very sensible, though not athletic, shoes with lots of toe room.
Which type of specialist should I be sticking with? (Everyone tells me to go to someone else and now I have come full circle)
Does this sound like anything you've heard of? If so, what?
How treat it? 68 yrs. 113 lbs, 5'2" Excellent health. Good circulation. Active. No diabeties.