Aa
Insulin Resistance?
How do you guys deal with this? I go hypoglycemic so easy...
Hello Skidue and welcome to MedHelp's Cirrhosis of the Liver community!
The determined cause of your cirrhosis is it NASH/NAFLD?
NASH (nonalcoholic steatohepatitis) caused by long standing obesity, type 2 diabetes, and insulin resistance. Non alcoholic steatohepatitis (NASH) is a more advanced form of NAFLD
While the natural clinical history and the processes involved in the development of NAFLD are beginning to slowly unravel, no single truly effective treatment has been found to date. However, common sense dictates that weight loss, if overweight, and correcting elevated cholesterol, triglycerides, and blood sugar should be beneficial in NAFLD
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Cirrhosis causes insulin resistance, a primary feature in type 2 diabetes. As insulin resistance progresses, it causes excess glucose to buildup in the blood, which leads to type 2 diabetes. Type 2 diabetes is also a risk factor for nonalcoholic fatty liver disease, one of the causes of cirrhosis.
Type 2 diabetes is the most common form of diabetes, accounting for 90 - 95% of cases. In type 2 diabetes, the body does not respond properly to insulin, a condition known as insulin resistance. Insulin is a hormone produced by the pancreas that regulates how the body converts sugar (glucose) into energy.
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In view of the multiple processes involved in causing NASH, it may well be that many different classes of medications, as well as weight loss, will have beneficial effects. These drugs could conceivably include:
Insulin-sensitizing agents, such as the two new thiazolidinediones, pioglitazone (Actos) and rosiglitazone (Avandia), and metformin (Glucophage)
Medications that lower lipids such as statin drugs and Lopid
Drugs that improve blood flow, such as pentoxifylline (Trental)
Presumably, weight loss through exercise and diet modification along with insulin-sensitizing agents will help reverse fatty infiltration of the liver. The other therapies might be beneficial in slowing the processes of inflammation and scarring. A combination of therapies will probably be the most beneficial.
It is critical that you stop or slow the progression of cirrhosis. Registering with a transplant center will offer many benefits as well. It will allow you to receive the best treatment for your pending condition. A general doctor or even a specialist in a private practice atmosphere would not be able to supply you with the treatment you deserve. Here is some more information pertaining to your circumstance and survival rate post-transplant.
http://www.news-medical.net/news/20111215/Liver-transplantations-for-NASH-Cirrhosis-increase-dramatically.aspx
I hope this helps. Take care!
Randy
The determined cause of your cirrhosis is it NASH/NAFLD?
NASH (nonalcoholic steatohepatitis) caused by long standing obesity, type 2 diabetes, and insulin resistance. Non alcoholic steatohepatitis (NASH) is a more advanced form of NAFLD
While the natural clinical history and the processes involved in the development of NAFLD are beginning to slowly unravel, no single truly effective treatment has been found to date. However, common sense dictates that weight loss, if overweight, and correcting elevated cholesterol, triglycerides, and blood sugar should be beneficial in NAFLD
----------------------------------------------------------------------------------------------------
Cirrhosis causes insulin resistance, a primary feature in type 2 diabetes. As insulin resistance progresses, it causes excess glucose to buildup in the blood, which leads to type 2 diabetes. Type 2 diabetes is also a risk factor for nonalcoholic fatty liver disease, one of the causes of cirrhosis.
Type 2 diabetes is the most common form of diabetes, accounting for 90 - 95% of cases. In type 2 diabetes, the body does not respond properly to insulin, a condition known as insulin resistance. Insulin is a hormone produced by the pancreas that regulates how the body converts sugar (glucose) into energy.
----------------------------------------------------------------------------------------------------
In view of the multiple processes involved in causing NASH, it may well be that many different classes of medications, as well as weight loss, will have beneficial effects. These drugs could conceivably include:
Insulin-sensitizing agents, such as the two new thiazolidinediones, pioglitazone (Actos) and rosiglitazone (Avandia), and metformin (Glucophage)
Medications that lower lipids such as statin drugs and Lopid
Drugs that improve blood flow, such as pentoxifylline (Trental)
Presumably, weight loss through exercise and diet modification along with insulin-sensitizing agents will help reverse fatty infiltration of the liver. The other therapies might be beneficial in slowing the processes of inflammation and scarring. A combination of therapies will probably be the most beneficial.
It is critical that you stop or slow the progression of cirrhosis. Registering with a transplant center will offer many benefits as well. It will allow you to receive the best treatment for your pending condition. A general doctor or even a specialist in a private practice atmosphere would not be able to supply you with the treatment you deserve. Here is some more information pertaining to your circumstance and survival rate post-transplant.
http://www.news-medical.net/news/20111215/Liver-transplantations-for-NASH-Cirrhosis-increase-dramatically.aspx
I hope this helps. Take care!
Randy
I was just reading through some of your other posts and then realized you haven't recieved a diagnosis yet, that my friend will make most of my post VOID with this being the case. Sorry I couldn't help. You might take a look at MedHelp's Diabetes forum where they may have answers more pertaining to your problem. All the best to you!
http://www.medhelp.org/forums/Diabetes---Adult-Type-II/show/46
http://www.medhelp.org/forums/Diabetes---Adult-Type-II/show/46
How do you know you're "hypoglycemic"? Do experience symptoms that are commonly associated with hypoglycemia? Have you ever measured your blood glucose with a home meter, especially when you're feeling hypoglycemic?
COMMUNITY LEADER
hello,
It would be useful if you can get a home meter and test when you're feeling like this to see if you really are hypoglycaemic.
To address hypoglycaemia, small frequent meals. Make sure these meals include protein and fat, which will slow the absorption and help stabilise blood sugar.
if you have hypoglycaemia secondary to insulin resistance it is important to strictly control carbs (particularly high Glycaemic index foods / white foods / sugars) as these will cause rebound hypoglycaemia (they require a lot of insulin to digest and after that you will go low).
If you are feeliung low and want sugar to bring you up, you need to keep that amount of sugars small (it doesn't take much sugar to bring blood glucose up). Ie. 1 - 2 pieces of candy, 1 single teaspoon of sugar, 1/4 cup of juice.
Have you been checked for diabetes? fasting blood glucose should be tested, along with HBA1c.
Hope this helps.
It would be useful if you can get a home meter and test when you're feeling like this to see if you really are hypoglycaemic.
To address hypoglycaemia, small frequent meals. Make sure these meals include protein and fat, which will slow the absorption and help stabilise blood sugar.
if you have hypoglycaemia secondary to insulin resistance it is important to strictly control carbs (particularly high Glycaemic index foods / white foods / sugars) as these will cause rebound hypoglycaemia (they require a lot of insulin to digest and after that you will go low).
If you are feeliung low and want sugar to bring you up, you need to keep that amount of sugars small (it doesn't take much sugar to bring blood glucose up). Ie. 1 - 2 pieces of candy, 1 single teaspoon of sugar, 1/4 cup of juice.
Have you been checked for diabetes? fasting blood glucose should be tested, along with HBA1c.
Hope this helps.
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