Does anyone have any information on the clinical significance of the A/G ratio? I have just recently added this test to our chemistry panel due to medicare requirements and am kind of fuzzy on the definition. My books don't offer much information.
Any information would be appreciated.
The albumin/globulin ratio is the calculation of serum albumin compare to serum globulin level to determine whether there is an overproduction or underproduction of gamma-globulin. A low A/G ratio may be due to overproduction of gamma-globulin (monoclonal/polyclonal gammopathy, multiple myeloma or autoimmune diseases etc.) or due to low albumin (low production as in cirrhosis or excessive loss as in nephrotic syndrome or protein losing enteropathy etc.).In contrast, if the A/G ratio is high then one should look for diseases with low gamma-globulin production such as agammaglobuminemia. Often a serum electrophoresis or immunoelectrophoresis can determine a more specific abnormality.
This information is provided for educational pirposes only.
Copyright 1994-2018MedHelp.All rights reserved. MedHelp is a division of Vitals Consumer Services, LLC.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.