I am 40 years old and have had heartburn for years. I took Zantac most of the time. Three years ago I went the doctor for heartburn and gas, mostly burping, they perscribed me to Nexium. I took this for 2 years which controlled my heartburn and gas. For the past year I have been taking Zantac. Three months ago on vacation I had severe heartburn and gas, the Zantac would not stop the symptoms. I went to the doctor again and he perscribed Aciphex, which I took for 10 days, but then I was having bad side effects, such as cramping, nausia, etc. At that time he had an ultra-sound on my gull bladder and he started me on Prevacid. My heartburn went away, but I am still gassy and now my stomache has been growling alot, whether I am standing, sitting or sleeping I can still feel it. I went back to the doctor for the third time in which they ran a series of tests. I had an upper endoscupy, EKG of my heart, stool sample, urine sample, several X-Rays, and many blood tests done. Everything came back negetive, except for a mild case of GERD. I have normal bowel movements. it does not make a difference on what I eat or drink, it never goes away. So my questions are: Why am I so gassy (mostly burping) and why is my stomache growling alot? On my fourth visit to the doctor he informed me that he thinks that maybe it is cause from stress. I have been under stress my whole life and have never in the past had these symptoms, therefore I know this is not the problem. Several years ago, after coming home from a hunting trip, I had somewhat of the same symptoms and at that time the doctor perscribed me an antibiotic, he felt I had some kind of an infection in my stomache. After taking the antibiotics for 2 weeks the problem went away. I have no idea what would be causing this, but I know I would like to see a doctor to be able to tell me what exactly is wrong with me.