Hello - thanks for asking your question.
Pain after cholecystectomy is a known entity (please see my previous answers regarding Post-cholecystectomy syndrome).
If there are stones remaining in the duct, a procedure known as an ERCP is commonly done by a gastroenterologist. This will identify and remove stones in the duct. If, after a complete evaluation (including an ERCP with sphincterotomy), a patient continues to have debilitating, intermittent RUQ pain, and no diagnosis is found, the procedure of choice after a normal exploratory laparotomy is a transduodenal sphincteroplasty.
Here are some adverse effects of PegInterferon from the Drug Information Handbook:
"ADVERSE REACTIONS >10% : Central nervous system: Headache (56%), fatigue (52%), depression (16% to 29%), anxiety/emotional liability/irritability (28%), insomnia (23%), fever (22%), dizziness (12%), impaired concentration (5% to 12%), pain (12%) Dermatologic: Alopecia (22%), pruritus (12%), dry skin (11%) Gastrointestinal: Nausea (26%), anorexia (20%), diarrhea (18%), abdominal pain (15%), weight loss (11%) Local: Injection site inflammation/reaction (47%), Neuromuscular & skeletal: Musculoskeletal pain (56%), myalgia (38% to 42%), rigors (23% to 45%) Respiratory: Epistaxis (14%), nasopharyngitis (11%) Miscellaneous: Flu-like syndrome (46%), viral infection (11%)"
As you can see, abdominal pain is a potential adverse effect. However, there are plenty of other reasons for RUQ pain and this should be explored with your personal physician. I strongly suggest followup.
I stress that this answer is not intended as and does not substitute for medical advice - please see your personal physician for further evaluation of your individual case.
in most cases stones in the duct after gallbladder surgery can be removed fairly simply by passing a scope through the mouth, into the stomach and intestine, and finding the duct where it joins the intestine. The stone can be extracted that way; it is "non surgical" and usually doesn't require overnight in the hospital.
thank you both so much for you answers...It really helped.
That's generally what they do if the gallstone is near the mouth of the bilary duct.