Aa
Aa
A
A
A
Close
Avatar universal

Adverse Effects in Dog After Prednisone


My vet prescribed 20 MG of Prednisone Q12H last week. Immediately my dog appeared to be having an adverse reaction.. as he was panting, nervous and shaking. I spoke with my vet and I tapered down... but he's still panting tonight and it is worrying me. Anything I can do to help him in the meantime ?  As far as his diagnosis, we still aren't sure but have ruled out many other possible health conditions. My vet thinks it is inflammatory bowel disease and our next step is ordering more tests, including a stool culture this time.

Thanks for your help.
31 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Two comments (This is a long comment, but I do get to prednisone, trust me) : #1 I have a 12 Y/O Jack Russell, and had noted that after rabies shots she got VERY sick.

I had even warned the vets years back that she had a reaction to rabies shots (especially the two-year variety). All the vets (three different ones, different practices, different cities) pooh poohed my diagnosis that the rabies vaccination caused an allergic reaction.

Part of the problem is that the dose for a teacup poodle is the same as the dose for a great dane. The same amount of vaccine is given to both. And they are killing our dogs with this stuff. No research, just stupid laws based on when someone somewhere may have got bitten by a rabid **** and had to take the shots. Horror stories. But search your mind. Do you personally know anyone in the past 50 years who has had to have the series of rabies shots?

After the last rabies vaccination given to my dog, the vet said that her sickness was caused by something else. After about $400 in blood work and urinalysis, he says, "Voila! Pancreatitis!" and he immediately gives her a prednisone shot and sends me home with oral prednisone.

I told him I would not accept that her condition was not caused by the rabies vaccination.

The fact of the matter was: First the vaccination, then the Pancreatitis: Action/Reaction.

I was told this was a condition that would be with her for the rest of her life, and I was sent home with hundreds of dollars of medicine, PRESCRIPTION ONLY food, and other handsfull of literature.

So I got home and googled "rabies vaccination pancreatitis." Believe it or not, I got about 3 million hits.

I sorted down and could easily tell that my case was not an isolated event, nor was it my imagination. When I saw the vet next, he told me that it was hogwash, and that I should not go on the Internet.

In our county a vet can exempt your dog from the vaccinations, and I demanded that he sign the document and send it in. He begrudgingly did it, but didn't like doing it and made that clear.

I contend that I probably know more about my dog than the vet does. I am with her 24/7. I know all the nuances, when she is not feeling well, and when she is in trouble.

#2) Segue to a new condition a few years later. I had been taking her to a dog park and one morning she jumps off the bed and falls flat on he face. She is walking into the walls. When she did her little shake, the force of the shake would throw her off her feet.  

I took in to see the vet. He quickly diagnosed her with "Old Dog Vestibular Disease." Her eyes were darting back and forth rapidly. This condition can be due to an inner ear infection, which I think was the cause and something that she picked up at the dog park, because there were other dogs there with balance issues. It is usually not serious and clears up in a few days.

Treatments that I see online include motion sickness medicine (such as Dramamine), and perhaps antibiotics for an infection.

After $600 in bloodwork, a full-body X-Ray, urinalysis, he gave her a shot of prednisone and sent me home with a bottle of prednisone pills with the following instructions: Give twice daily until gone. There were about 40 of them in the bottle. This as March 1, 2017. When the bloodwork came back, she had normal glucose levels. That was before the prednisone.

I had to go out west for a couple of months and when I got there, she was really sick. I actually checked her during the night because I was afraid she was going to stop breathing.

I took her to a 24/7 Veterinarian Clinic in Las Vegas. Once again, bloodwork. When the results came back (the following day, they called me at home, said she had diabetes and I needed to bring her in right away).

The two blood tests were five weeks apart, and in between was the induction of prednisone as described above.

I have now googled "diabetes in dogs prednisone,"  and guess what? I am convinced that the random introduction of preednisone into my dog's system actually CAUSED the diabetes.

I again told that vet what I found and he again said, "Hog Wash!" Plus he said, people are always trying to blame the vet on what happens with their animals. He was annoyed and just the fact that I brought up what I found made him mad.

I wasn't blaming, I just wanted to discuss the matter and find the best course of action to take.

No vet will acknowledge this, just as no dentist will acknowledge that mercury fillings are dangerous. (If they did, that would be the class action lawsuit to end all class action lawsuits).

I am struggling now trying to regulate the insulin levels for my dog. It will be a lifelong task with her.

I write this to put it on the record that: rabies vaccinations can cause pancreatitis and that prednisone can cause diabetes in dogs.

Beware!

It is a fact. We over-vaccinate our animals, and sometimes those vaccinations are killing them.
Helpful - 0
1 Comments
My Westi, 11 years old, had his three year rabies shot  teeth cleaned and three removed, and about two weeks later got pancrititas. Do you think the rabies shot caused it, bring two weeks later?
Avatar universal
Yes. The same thing. My 9 and a half year old boxer has been on 20 mg twice daily for 15 days now. She has been wetting her bed, panting.  She has a joint infection and needs the steroids to control her fever. When she tappers down the fever shoots back up to 104.6.  This has been horrible. Getting up 3 times a night to let her out and she has already wet her bed. Hopefully it will stop after her dose gets lowered by the way, she is only 54 lbs
Helpful - 0
Avatar universal
We lost our 6 year old boxer November 1. He was prescribed prednisone for an ear infection in mid-October, and aside from that was a healthy, happy dog.  He immediately started with the common side effects (panting, excessive thirst, eating everything he could fit in his mouth, etc.), but our real concern came when he started to collapse out of nowhere almost a week after starting the medication. We weren't sure what was wrong, and it took two more trips to the vet to find out that he was becoming severely anemic very rapidly. It turned out that his stomach had ulcerated, another side effect of the prednisone. By the time we figured it out though, it was too late. His RBC count was falling too rapidly and even with a transfusion or surgery, the chance that he would recover was not great.

I just want to warn everyone. Please please please do your research when starting your pet on a new drug. Know the side effects. Read about how it works. Veterinarians are so busy, many don't have the time to explain the risks to you fully. My biggest regret is that we didn't read up about prednisone before putting our dog on it. If he wouldn't have started that prescription, he would still be here today.
Helpful - 0
Avatar universal
My pup is 10 months old and 4 weeks ago we nearly lost him. We found him lying underneath the table in a pool of drool, couldn't walk and put it down to a rawhide shoe we have given him the night before. He spent the evening at the vets and we thought we were going to lose him. Luckily he pulled through but seemed to be suffering from what looked like meningitis (yelped with certain movements, rigid standing etc) and consequently is on prednisone. His dosage was 35mg daily (he is 20 kilos / 45 lbs). I rushed into prednisone, it literally saved his life and I had no option to read about the pros and cons beforehand. Now I'm reading all this stuff, seeing him panting, eating EVERYTHING, moody, not his usual playful self and to learn that prednisone can cause cushings disease amoungst other things really worries me. I guess we have to put our trust in the professionals. We are in the slow process of taking him off the steroids now and praying his symptoms don't come back. I will however be inquiring about an alternative method of treatment with less side effects. Good luck to everyone and their pups, it's heartbreaking when they get ill and its beyond our control x
Helpful - 0
Avatar universal
Reading this old thread amazed me at how many people use, and vets prescribe, prednisolone, for long term, or multiple use. The only time I've used it was with two of my dogs who where terminal with cancer. And then it was only in their last few weeks just to make them more comfortable and give them (and me) a little more time.

Myself, if convinced it would help 'get to' a positive result after ONE prescription, then I would buy it, but only then. It is a STEROID folks. Have you ever seen 'roid rage' in a person? It's like a Dr. Jekyl and Mr. Hyde. Not good. I would have to think the more consumed, the worse it is on the body.

Look for alternatives, people, don't be so quick to just put into your animal what the vet says. Know what it is, what it does, good and bad, and weigh out the cost/benefit ratio. This comes from spending the time researching.

If your pet is not worth expending the effort to learn, and not be at the complete mercy of what your vet thinks is the solution, then maybe you should not have a pet.

As for long term use, I just don't see how subjecting an animal to the damage that it does offers an improvement long term. Personally, if my dog was ill or miserable enough that steroids were needed 'long term', I would seriously have to consider just putting them to sleep.

As far as the dosages, when first prescribed for my terminal dogs, even then I only gave them 1/2 of the dosage, which minimized any possible reactions, and allowed for a longer tampering off period.

Sorry for the rant, I get passionate.
Helpful - 0
3 Comments
Kirk- my dog was only recently diagnosed with IBD which is why I am just reading your post now. I am concerned about giving my dog steroids and, like most of these people, care enough to do the research to find alternatives. This forum is most likely only one of their sources. Unfortunately there doesn't seem to be many options, so instead of ranting and telling us all we don't deserve our pets perhaps you should try offering a more appropriate solution. If you don't have one, which seems to be the case, perhaps you should refrain from commenting at all, especially if you can't be positive. To suggest putting our pets to sleep, pets that are systematic but not lacking quality of life, is cruel and inhumane. As far as treating my dog, no this forum didn't offer any alternatives to long term steroid use for IBD, but it did remind me to follow my instincts and to question my vet when necessary, and I'm grateful for that.
Wow, some of us have tried everything. Some of us have an animal with multiple autoimmune diseases. Some of us are devastated at what these diseases do to our fur babies and will try anything to give them a happy life. after many hours of research and tests and tears, and specialists, prednisone is the only that works. So maybe you turn your "passion" to compassion or just shut the hell up all together. Thanks!
kerk2 - I'm gonna call you out on your B***S***...  First of all, if you, your SELF had 'expended the effort to learn' what your vet had just prescribed a dying animal, you wouldn't have done it. Prednisolone is the LAST thing I would give to a dog to make him feel 'more comfortable', as that is the exact opposite of the expected result. If the dog had a fighting chance of beating the cancer, then maybe, but he certainly wouldn't be 'more comfortable' in the process.
Second, if you, your SELF had 'expended the effort to learn' what you were giving your animals, you would also know that the 'roid rage' you speak of is associated with ANABOLIC STEROIDS, which are similar to testosterone. Prednisolone is a CORTICOSTEROID, which is meant to regulate physiological functions. It can cause irritability, and mood swings, but not 'roid rage'.
Third, if you thought your terminally ill dags were going to experience 'roid rage', than how, the F***, did you think that would make them 'more comfortable' on their death beds.

I am not defending this drug BTW, Prednisolone is some HORRIBLE ****, that should NEVER be given to an animal that can't tell you what they experiencing as a result. At least whenever there are any alternatives.

The fact is that most steroids are grossly over prescribed, under evaluated, and down right dangerous.
Avatar universal
My 6 yr old boxer is on prednisolone for the past 5 days. 31/2 tablets 2 x/ day for bronchitis. He's panting all the time, drinking lots of water and peeing a whole lot. This morning he has started peeing himself while lying down or sleeping. The pee just runs out. I spoke to my vet and he said to just stop giving him the prednisolone completely. Has anyone else had this peeing while lying down or asleep issue?
Helpful - 0
Avatar universal
My 11 yr old golden is on prednisone for a second round,  so this has been 2 months, all due to a hematoma in her ear  The first time I tapered down like vet said and she was too crazy and hungry so they let me stop during the tapered down week.  Then the hematoma came back so they restarted it for another month, now on the taper down weeks of every other day.  She was heavy panting and anxious, hyper.  Past 24 hours has diarrhea and very tired.   Didnt eat dinner, highly unusual.  
Helpful - 0
Avatar universal
Has your dog improved? My 65lb Shepard mix is on prednisone after an injection to treat heartworm. She is on day 6 at 30mg a day. Her behavior has changed and she's panting like crazy tonight with a runny nose.
Helpful - 0
2 Comments
How did your dog end up doing? My 70lb lab mix is on prednisone and doxycycline because he tested positive for heartworms
How did your dog end up doing? My 70lb lab mix is on prednisone and doxycycline because he tested positive for heartworms
Avatar universal
Our lab that is 90lbs & 11 yrs old is also on predinisone and having panting spells.  She has allergies.  She is now down to 5 mill a day.  Is the panting a side effect?
Helpful - 0
Avatar universal
Our lab that is 90lbs & 11 yrs old is also on predinisone and having panting spells.  She has allergies.  She is now down to 5 mill a day.  Is the panting a side effect?
Helpful - 0
Avatar universal
I may be wrong here I have switched  vets also. My vet said my pup who is 5 and an American Bulldog would have to be on predinisone for the rest of his life. the new vet said he must get off the prednisone because it causes Cushings disease and he is on the verge of getting it. He had to put him on it becaue he broke out in hives but one a day for 3 days, a half a day for 3 days but with what it made him do I only have given him a half for 2 days. the I will do the half every other day. I hate steroids. Now this vet told me it takes a month for them to completely get out of their system.
Helpful - 0
Avatar universal
We DO pay for trained professionals but we don't always GET them.  After a local vet over scribed for my old dog I did some research.  The vet in his office and in their low cost spay and neuter clinic was NOT LICENSED!  You can search online and read any orders or punishments they've had.  

I turned in this group for using an unlicensed vet for surgery and vaccines!
Helpful - 0
Avatar universal
No they should not be vaccinated period. If you were to read the label on the vaccine it would state . " For use in healthy animals only" If the pet was on prednisone it would not be healthy.
Helpful - 0
Avatar universal
Can anyone help..... My Dads beloved dog of 13 years was given prednisolone for an itch and in the same visit was given a live vaccine.... he died 2 days later..... my question is should a dog on prednisolone be given a live vaccine????????????
Helpful - 0
Avatar universal
Be thankful it is oral. I took my 15 year old Jack Russell in for a "regular"allergy shot last Friday. I think my aging vet over dosed his shot. He has been lethargic, thirsty, not-eating and I think this has pushed him into having Cushings. We are just trying to keep him drinking and eating alittle and see if he comes out of it. Took him back to vets (saw a different one) and the physical exam showed distended gut, enlarged "chest" lymph nodes. He has a heart murmur that we knew about and they wanted to do blood work, etc. We have expected "the end" for awhile and just want him comfortable without more trauma as he hates the vets....wish us luck.
Helpful - 0
Avatar universal

I forgot to add that the ER vet said to keep him on 5 MG of Prednisone for a couple of more days. Next, she said to administer 10 MG by mouth once every other day for 2 doses. After that, she wants me to stop the medication completely.

I dread giving him more steriods, but I know that you have to be careful weaning and you need to do it right.

I just hate to see him having trouble breathing (it seems anyway) when he's sleeping... he even wheezed today (why? after steriods??) and he's still trembling and panting. But the panting is better and I just pray that he gets through this and is okay afterwards and then we can address his chronic diarrhea.
Helpful - 0
Avatar universal

Hi Karla & peekawho,

Thank you for your responses. Yes...  in my opinion, I think the vet accidentally doubled the dosage.

My dog is still panting, but I think he's getting a little bit better. I'll keep you guys posted. We are going to be taking him to another vet in a few days.... after we successfully wean him off the Prednisone.

Thanks again.. you guys are great !
Helpful - 0
462827 tn?1333168952
Damn!!!!  Don't be upset with yourself....We PAY, medically trained Vets to make these decisions for us...It's not your fault.....I got to thinking: Because maintaince doses are done every other day; that leads me to believe that it must stay in their system for up to 48hrs. Does that make sense?  Hang in there....And keep me posted....I'll be thinking about you...Karla
Helpful - 0
172023 tn?1334672284
If the prednisone has been stopped....the dog should quiet down relatively quickly.  Like, within 48 hours he should be pretty much back to normal.

Our dog was on 20 mg twice a day, and he's 70 pounds.  And THAT was too much for him (and us) to cope with the frantic side effects and peeing.

Helpful - 0
Avatar universal

Hi ! Thank you for your note. I would have responded earlier, but we took my dog back to the vet... actually the ER. He is still panting like crazy and he's been panting so much that the vet couldn't even listen to his heart and/or run really any tests. They said that it is probably still the Prednisone, but to monitor his condition closely and then follow-up for additional testing. Obviously I'm not taking him back to that other vet ever again.

I am so upset with that vet because I think she overdosed him and I'm uspet with myself because I almost questioned the dosage and I didn't.
Helpful - 0
462827 tn?1333168952
Whew!!!  Yes, I worried about him all night...I'm so glad he's better....I was basing my response on a 16lb. dog that took 5mg. 2@day. Then 5mg. every other day as a maintaince dose. (For what we thought was IBD, also).  *Steroids cause excessive thirst, frequent urination, and excessive hunger. IMO, the panting, nervousness, shaking, means the dose is too high. It's just like "Speed". The heart races and it's dangerous...In a Senior, your more likely to have "heart failure" as the heart cannot tolerate this sudden onset of rapid beating for too long.....I have a heart failure furkid and I know the risk of him taking Pred. The risk outweighs the benefits of the medication...Anyway, I'm glad your both better and keep us posted.......Karla
Helpful - 0
Avatar universal

Poor guy... that's terrible ! My other dog, who died from ITP only 2 weeks after getting her second Parvo vaccination, had a stomach ulcer from Prednisone. She ended up bleeding out of course because of the ITP and we spent thousands of dollars trying to save her, but it didn't work. It was heartbreaking. I just dread the day when I lose my boy... he's my buddie and my first dog ever. I've had him since he was a puppy.
Helpful - 0
172023 tn?1334672284
We had to put our dog in diapers, he peed all over the place, running around dribbling everywhere when he was on Prednisone.
Helpful - 0
Avatar universal

I know... the new vet screwed up. I just didn't want to go there last night because I'm still upset. I had already taken him to a specialist and even questioned her about the dosage... that is why I immediately tapered down. When I got the original prescription, I thought that was an awfully high dosage, but I didn't question her and I regret it. My dog is still upset with me. (no joking either).

He's doing better today... but still has a little bit of shaking. Thank goodness. I didn't sleep well last night because I was so concerned about it.

I'm probably going to be switching vets... but the vet sounded apologetic last night when I spoke with her about this. She now wants him to take 10 MG every other day... that sounds reasonable, but I'm going to give him a break first.

We still don't have a diagnosis, but we've ruled out many conditions.... including all of those (tick fever, valley fever, etc.) where steriods would make him worse. He has chronic diarrhea and has had this condition since he was a puppy... but it has gotten worse. But in all honesty... no other symptoms. Everyone tells me that he looks and acts like a puppy... he still plays with his adopted sister, who is a very big puppy (and will always be... LOL!)
Helpful - 0
2
Have an Answer?

You are reading content posted in the Dogs Community

Top Dogs Answerers
675347 tn?1365460645
United Kingdom
974371 tn?1424653129
Central Valley, CA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Members of our Pet Communities share their Halloween pet photos.
Like to travel but hate to leave your pooch at home? Dr. Carol Osborne talks tips on how (and where!) to take a trip with your pampered pet
Ooh and aah your way through these too-cute photos of MedHelp members' best friends
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.