My Honey is a 4 year old Golden Doodle. I have two other dogs Hannah 5 year old Golden Doodle, and Dakota who is a 5 month old mixed Rottie/Mastiff pup. Honey always played with Hannah and Dakota, now she is on the sofa and won't come down unless you take her out and try and feed her. All my dogs eat one of the top notch dog food's you can buy Fromm, Gold for Large Breed Dogs. She will not eat it, I have been cooking hamburger and rice, chicken and rice, and she will eat this. She is having bowel movements regular and peeing, so no blockages or UTI's. She was in her heat cycle and needs to be spayed, and no she is never near another male dog to be pregnant. When my dogs go out...They are always a leash, never left out of my sight. I also noticed she was limping on her hind leg, and holding it up. Put her on Doggy buffered aspirin for two days now and still having problems on and off. Second part of problem is with her heat cycles...she does not have normal heat cycles and yes I know she needs to be spayed. That is being done within the next week I hope. Not sure what could be causing her problems with no eating and being lethargic.