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Dry Eye - KCS - anyone prescribed Sirolimus?
Hi,
Our dog was diagnosed with dry eye a little over 6 weeks ago. Both eyes had a schirmer test of 0. (interestingly though, a few days before at the vet, the schirmer test was 12 in both eyes). Now 6 weeks later, the right eye has a 6 and the left eye still has 0. The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet. Also, it's $95! Anyone have any experience with this? Anyone whose pup responded to cyclosporine after not responding to tacro?
Our dog was diagnosed with dry eye a little over 6 weeks ago. Both eyes had a schirmer test of 0. (interestingly though, a few days before at the vet, the schirmer test was 12 in both eyes). Now 6 weeks later, the right eye has a 6 and the left eye still has 0. The specialist reviewed all of the options with us - cyclosporine, pilocarpine or tacrolimus with sirolimus. She said that very rarely has she seen any dog respond to cyclosporine after not responding to tacrolimus. She also said that because our dog doesn't have a dry, goopy nose, that pilocarpine wouldn't be a first choice. She recommended a mix of tacrolimus with sirolimus. She said sirolimus is new. I have not been able to find anything about this drug on the internet. Also, it's $95! Anyone have any experience with this? Anyone whose pup responded to cyclosporine after not responding to tacro?
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