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Avatar universal

scopolamine withdrawal

I have a complicated question.  I was given a scopolomine patch for surgery.  I was hospitalized for 4 days.  About 48 hours after I was discharged, I began suffering from significant nausea and vertigo.  My OB\GYN surgeon prescribed more scopolomine patches. I also developed severe sinusitis and bronchitis in the week after my discharge and was put on an antibiotic.  Each time I used the patch, the symptoms were controlled, but about 24-48 hours after removal, the symptoms were back with a vengeance.  I called after the third patch, and my surgeon said I needed to see my PCP because it was no longer surgery related.  I asked whether I was having some sort of "rebound" symptoms from the removal of my patch, and she told me no. I went to my pCP, he believed it was an inner ear problem,  gave me another round of antibiotics, a steroid shot, a medrol dose pack and two more patches in  case the symptoms came beck before the meds worked.  I continue to have the same problems.  With my own research, I am reading that my symptoms may well be withdrawal from my scopolomine patch.  My question is whether this sounds like what may be causing my problem and if so, now what?  What is the best course of action to get through the incapacitating symptoms and get off this patch?
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Avatar universal
Thank God for these posts! I thought I was going crazy! I went on a 5 day cruise- Dec.19-24. I put the patch on the first night and another one 2 1/2 days later. On Thursday morning (24th) I took off the patch and WOW- that night the symptoms really hit me. All the same as everyone else- nausea, lightheaded, EXTREME fatigue, and generally out of it mentally. Why didn't the doctor tell me ANY of this could happen? This is hell. There are so many different stories on how long this will last- it is really scary (and depressing) I am hesitant to begin the other meds (meclizine) as I think I'd rather try and "detox" all at once. I've already made it through 3 days without anything- does anyone know how much longer the symptoms last. I only used 2 dumb patches- how could they have been so harmful????
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Avatar universal
It February 22nd, 2019.. I was a Cruise Director for a casino cruise ship that sailed 2x/day - 7 days a week. I was prescribed Transderm-Scop for my seasickness. I was on the patch for my 5 day a week work schedule 3 months.  On my 2 days off each week I began suffering with debilitating migraines for both days. Upon going back to work and reapplying the patch I would feel fine again. I never connected the dots! I don't smoke, drink or do drugs, so I know nothing about addiction.

My migraines transitioned and snowballed into vertigo, killer pounding headaches, eye pressure, body sweating then freezing, stability and balance issues, nausea, sensitivity to light, lightheadedness,  excruciating neck pain to where I can no longer hold my head up.

I recently saw a neurologist who scheduled a cervical spine MRI that revealed typical arthritic aging. Nothing remarkable. She dismissed my case bc she thought that I was a hypochondriac. She actually yelled at me.

I've never had a history of headaches or migraines. I'm your happy, fun Cruise Director! Knowing thsee symptoms were uncharacteristic I contacted the Mayo Clinic and was seen immediately and given an immediate MRI on my brain that again, revealed nothing. My neurologist is baffled. I came home from the Mayo Clinic 2 days ago and started doing some research on the Transderm-Scop patch and found this forum.

It seems we are all suffering the same exact withdrawals and side effects from this dangerous drug. I'm so glad I found this forum. My concern is how long will these withdrawals persist?  I have been out if work for 4 weeks... my mom has had to take care of me!  I'm 55 years old.. this is not acceptable but I'm incapacitated. I can't lift my head off the pillow... on a good day I'll make it to the couch.

I'm going to try to get a script for Meclazine and Zofran. Hopefully I will soon see some relief. I've been taking Butalb (Fioricet -for my migraines) like they're M&Ms..

The hardest part is most doctors do not realize what Scopolomine Withdrawals are. This is very serious and debilitating. This forum started on 2008... it's now 2019.. clearly the FDA listens to its consumers. NOT.

I will never use that patch again. And I'm hoping I'm not looking at years and years of this drug's residue remaining in my system.
Helpful - 1
2 Comments
Cruisedirector, I understand your frustrations and there is no real good advice I can give you.  No doctors at all know anything about Scopolamine withdrawal syndrome and completely dismiss it.  There is no way to know how long you will have withdrawals as there have been no studies done on use over 72 hours or follow up after patch use. The withdrawals last a different amount of time for each person. Some vision changes can be permanent.  All I can say is don't let them dismiss the patch. It is the reason for your symptoms. Take Care
Hi I am going through these exact symptoms right now , loss of balance , blurred vision , room swaying , ear pressure, and severe anxiety. I’ve been out for over a week and have cold turkey the scopolamine patch that I was using for 6 days , I had to add another patch in between the week since one fell off so clearly I had way to much in my system . I have not used any meds since being off it and have stopped taking my daily medications as well to get this to get out of me .

How did you cope and manage for so long and when does it start to subside .
Avatar universal
I would love to speak to anyone on here that I'd still active.  My husband was on a Scopolamine patch for 2 years!!  He's been suffering long term withdrawls now for the last 2 years since he took it off.  Gina are you still trying to get off the patch?
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4 Comments
What kind of symptoms is he having?
He's having what we believe to be long term Scopolamine withdrawal syndrome.  He's fine for days, sometimes up to 3 weeks, then he gets itchy or sweaty mainly his hands/Arms and legs, then super nauseous and really bad vertigo, abdominal pain, vomiting, than after all that he gets confused, agitated, paranoid and sometimes delusional.  These episodes started the first time we took the patch off, and have been happening atleast once a month for 2 years and 2 months.  He's been on no other meds either for 2 years.  
That’s terrible. What does his doctor say?   Why did they let him stay on it for so long ?
They thought it was helping his nausea, but it was actually causing it.  It's a long story and no doctors no what to think about it.  Using it that long is unheard of!
Avatar universal
8 days.   I’m down to 25 mg every 8 hours. I too scapolimine for three minutes baths so it is going to take a while.    
Helpful - 0
8 Comments
Sorry for the typos.  From what I have read on the internet , it could take a while because I was taking scapolimine for 3 months. I am hopeful because I’m decreasing the meklazine.    I feel so much better on the meklazine.  I don’t feel nauseous and sick.  I’m syarting to feel more like myself.   My ENT sent me to a neurologist.  The neurologist said to get off the meds and take the meklazine
It expireseems today at 9pm and I'm so scared with my nerves bad. Should I leave it on and start the meclizine or take it off? I'm very upset with the surgeon that put me on the patch. So my family doctor gave me da meclizine 25mg because I seen so many people on here saying 25mg. And I left a message for my family doctor to send zofran for me to the pharmacy for today. What do you think I should do? Thanks so much for your help
I took the patch off first.  There is a reserve in the patch.  About 4 hours later, or if you start feeling bad take 50mg meklazine every 6-8 hours    My dr said do it for 3 days then taper down.  You may be able to taper faster.  Hang in there.  The meklazine will keep you from being sick
I took the patch off and started already. I will let you know how it works for me. Thank you so much I've been depressed all day
Don’t  worry, you will start to feel better soon.  How long were you on the patch?
I am hoping to be off the meklazine by next week.    That will make a total of three weeks on the meklazine.  I’m finally starting to feel like myself.  I’m taking 25 mg every 12-14 hours.  .. Just  make sure you keep ahead of the medication and you will be okay
I was on the patch for 2 months. I tried the meclizine all day yesterday till 10pm and was still sick. I think the problem is I only have 25mg meclizine . I'm wondering if the surgeon who did my surgery and put me on the patch can just get me admitted to the hospital. This Is really hard considering the pain in the stomache that it gives me. How long were you on? I was on 2 months
I took two pills 2x 25 as per instructions by my dr. From what I have read 25 isn’t enough.   Talk to your dr.
Avatar universal
The dr told me about meklazine.   It’s the prescription form of Bonine.    It called the meklazine taper.   Works great. I was so sick from the scapolimine when I took off the patch.  I started taking 50 mg of meklazine every 6-8 hours for 3 days then taper down   I’m still on 25 mg every 8 hours.  Good luck
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8 Comments
Hello, I have the meclazine and im on my last patch im so stressed. So do u think the meclazine will work for me? I have 25mg do you think I should get 50mg? Im so stressed and once I take the patch off im so sick.
How long have u been on the meclazine?
I would suggest taking off the oatch and waiting  a bit, to get it out of your system.  Then before you start feeling bad, take 50 mg of meklazine.  I also had nausea meds that I could put under my tongue.   The meklazine will relax you and you will not feel sick.  
Are the pills for under the tongue prescribed or can I get them over the counter. Thank you so much for replying.
They are prescription. Zolfran   Works like a charm in 10 minutes.  The trick is to stay on top of the meklazine.  50 mg 6-8 hours.    You can’t drive and your vision is a bit blurred because your eyes will dialate.   Now that I’m on 25 every 8 hours I can work and drive. Every one is different.  I’m trying now to go as long as I can between doses.  Today I’m trying 9-10 hours.  I have my zolfran nearby in case I start feeling bad.   I immediately take one and one meklazine. The meklazine takes 30 minutes to get into your system.  Hang in there.  It will get better.  Talk to your dr.  Have him help you with the dose.
I send you a comment on the tread below.   I hope you got it.  Hang in there!!
Thank you so much, Im gonna ask my doctor for the zofran asap
Did you take off the patch yet?
Avatar universal
wow gina, I had surgery in march and never knew it was the patch till now. I was so sick yesterday. how can i get the hospital to admit me. I put on my last patch and im so scared once the 72hrs are up
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16630874 tn?1449850724
I have been on this patch for 3 1/2 years due to dr oversight. long-term used has caused medical problems (tachycardia, gastroparesis, blurred vision, SOB, really bad memory,etc. Two attempts to withdraw landed me in a er. going into the hospital to withdraw. I contacted a professor who did long-term scop use and he said no one has ever been on it as along as me. he anticipates a very long road. once done with the outpatient aspect *meclazine valium and zofran) I will continue to have episodes monthly for awhile. this drug enters the brain barrier. can't believe I am in this mess.
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3 Comments
I finally am off the patch it's been 9 months and I am so relieved. What a long scary road.
I had to be medically admitted in the hospital to be weaned off scop patch. I entered hospital on dy 4 of wearing the patch and was there for 6 days. Had two weeks of outpatient and valium type meds with meclazine and zofran and within 2 months I was off the meclazine. Just have an occasional dizzy spell and nausea but free from the patch
I had to be medically admitted in the hospital to be weaned off scop patch. I entered hospital on dy 4 of wearing the patch and was there for 6 days. Had two weeks of outpatient and valium type meds with meclazine and zofran and within 2 months I was off the meclazine. Just have an occasional dizzy spell and nausea but free from the patch
Avatar universal
I am so glad I found this forum!  I've been experiencing the exact same thing after using the patch for a four day cruise!  The cruise was 6 weeks ago and I have been sick ever since with all the same symptoms listed above!  I have seen 4 doctors, my family doctor, a chiropractor, a neurologist and my kidney specialist.  None of them mentioned this and I told all of them that I used the patch.  I have missed 5 weeks of work and I too thought I was going crazy.  What a horrible feeling.  I am going to get some meclizine ASAP.  It is only available in the US and I am in Canada so I will be going over soon to get some!  Thanks to everyone for showing me this can be fixed!
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1 Comments
Also, all of these drs diagnosed me with benign positional vertigo, which is clearly not what I have.
Avatar universal
I left it on for 5 days and developed a horrible rash behind my ear that took 2 weeks to heal. I too am an RN and have experienced the same symptoms as described above only I thought it was a reaction to anesthesia vs the scopolamine patch. After being referred to an ENT and being told I had migraines and was told to "take off my nurses hat" (when I questioned why the symptoms only occurred after surgery), I decided to research on my own BEFORE having another $1K  MRI. Glad I did because I thought I was going crazy and have been off work for 2 months. The Meclizine and Zofran  weaned me off the patch and physical therapy helped the vertigo but I'm still having problems focusing my eyes and with occasional slight vertigo. I have an eye doctor appointment next week and have cut my sodium intake. Sooooo glad I decided to research scopolamine withdrawal and found I'm not the only one. The anxiety and depression are very real and sadly not taken seriously by health care providers. I'll be sending this to my physicians in hopes of educating them.

  
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Avatar universal
I am currently going through this horrible patch withdrawal.  I used the patch every 3 days for a 14 day cruise.  Knowing about the patch withdrawal, I tapered down by covering 1/3 of the patch with a band aid, 3 days later covering 2/3.  After 3 days, I removed the patch completely.  By the next afternoon, I was completely incapacitated.  Dizzy and nauseous when standing.  In addition, I feel so depressed and anxiety ridden...like an impending sense of doom.  I have already missed nearly a week of work, which I am sure is contributing to my anxiety.  I am currently taking Meclazine...25 MG's 3 times a day, but based on what I am reading, may need to increase that.  No one tells you about what can happen after using this drug.  I can understand maybe feeling a bit under the weather, but this is extreme.  So hard to explain exactly what I am feeling.  It is overwhelming.  Trying to avoid taking anti-depressants on top of all of this, but feeling so nervous and depressed.  The patch works like a charm to avoid motion sickness, but the price you pay after is not worth it.  I love cruising but suffer from severe motion sickness.  This patch allowed me to enjoy a wonderful vacation, but never again.  This is a dangerous drug and the after effects are debilitating.  Stay away from the Scope Patch!
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2 Comments
Hi, I'm going through the exact symptoms as you were, can you help me. Can helped and in how long did all symptoms disappeared.
How long did it take for your withdrawal symptoms subside? I'm trying to taper off now.... The headache and dizziness is really getting me.
Avatar universal
Thank God for this forum and all of you! I just returned from a vacation with my wife, 3 yr old son, and sister-in-law. I took my last patch off early Tues afternoon. By Wed afternoon I was beginning to feel "off." On our bus ride to the airport late that afternoon I was really feeling bad. I was sweating bullets on an air conditioned bus and had severe motion sickness (even though buses NEVER bother me). I literally threw up within a minute or two of getting off the bus - thank God the bathrooms were right inside the airport doors. The flight home was terrible - I barely avoided throwing up. As soon as we got to my father-in-laws house (he picked us up) to get our vehicle I threw up (20 minutes from airport), as soon as we got home (another 20-30 min ride) I threw up again! Equilibrium off all night and still today, just walking around makes me a lil naseous. Without this forum I would still be wondering if I was experiencing withdrawal or something else?! I call my dr office (the one's who prescribed it) and two hours later still hadn't heard back! Called back and actually got a call back within 20 min - with ALL my info wrong! They had no flippin idea! This is ridiculous! Drs. prescribe a drug that can have such severe withdrawal symptoms AND they aren't even familiar with them - how the hell is that doing your profession due diligence?!
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Avatar universal
R2H
I used the patch for an 11-day cruise and experienced the same side effects 24 hours after removing the patch. It was awful and I thought I may have caught something while being oversees. I'm so grateful I found this discussion as it put my mind at ease. What really helped for me was wearing Sea Bands. I didn't want to take more medication so the Sea Bands were a safe and effective way to manage my symptoms. I wore them for 2-3 days and found that I no longer felt ill. I hope this tip will help someone suffering from the side effects post the patch.
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Avatar universal
Did you do anything to get better?  I wonder if I just go cold turkey and tough it out?
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Avatar universal
Hi Squast,
What kind of cream/steroid did you use to try to clear up the skin behind your ears??
My boyfriend is having the same problem with the skin behind his ears too and has been using just regular otc hydrocortisone cream.
Thanks
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Avatar universal
Hi Gina, hope I can still reach you so many years later. I had surgery 6 weeks ago and cannot get off scopolamine, causes unbearable nausea. Wish they never had put me on it. Do you think weaning the patch size would help getting rid of it? Or should I play with the length?
Thanks so much,
Krisztina
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Avatar universal
Just wanted to post an update. I only took two 50mg doses of Meclizine on Saturday - one in the morning, and one in the evening - after ripping the patch off "cold turkey" on Friday at lunch.  On Sunday, I awoke and took a 25mg dose. I felt slightly off in my head but not nauseous all day long. I took one last 25 mg dose before bed and WOKE UP MONDAY FEELING NORMAL!

I am so excited to be done with this mess. There you have it, folks. You too can be off this patch in only 2 days. With no nausea !
Helpful - 0
Avatar universal
I too got "tricked" into becoming patch dependent. I was given one preoperativley for a laparoscopic surgery about a month ago, then when I returned home, a few days later, the nausea returned with a vengeance. I innocently asked my Dr. for a refill on the patch and here I am one month later.

I have tried more than once to get off this evil patch with the same hellish symptoms posted above by everyone else, only to have to put another patch back on. One incident was so frightening I almost called an ambulance. Well I am posting today because I removed my patch yesterday (Friday) at 11 am and have experienced NO nausea since then. Thanks be to God. I am now past the 24 hour mark as I write this (it is 4:30 pm on Saturday afternoon).

I felt only slightly "off" before bed (about 8 hours post removal), so I didn't take the full 50 mg Meclizine. I decided only to take the 25mg dose. I woke up feeling a little but hungover (tired,heavy headed), but no nausea. I managed to take a shower and cook breakfast for my family. About 10am, I decided to go ahead and take the 50mg dose of Meclizine because I felt in my gut the nausea was headed my way. I laid down 30 minutes later because I started feeling sleepy. I slept all afternoon, through lunch, and awoke at 4pm and I feel relatively normal! Hungry, but not nauseous.

I plan to take another 50 mg before going to sleep tonight. I will let everyone know how it goes.

I just wanted to say that this patch is evil, I will never be using one again, and I CANNOT WAIT until I am a few days out from it. I will post updates. I was so grateful for everyone else's as I researched the best way to get off this thing.
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Avatar universal
I started the patch three cycles ago. I was on meclinzine before. But was up to taking 150mg daily. Way too much. . The patch is working great. But i did notice that I removed it last night.72 hour limit. And forgot to replace it with new one. Well it didn't take long for my vertigo and labrynthitis to kick back in today.. But as soon as I put new patch on within a few hours the dizziness and nauseas has lessened..
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Avatar universal
Mary,
It is good to get a physician's perspective on the use of the patch. Unlike many of the comments on this site, I used the patch for relief of major dizziness and nausea, to the point that I couldn't take my head off the pillow. Just going to the bathroom took a tremendous amount of effort since the "recovery" to get myself past the horrible throbbing head and nausea often took 2 hours. No one seems to have any explanation for my condition. The patch has been a life saver. Unfortunately, like others posting, I can't seem to live without it now. How bad is the medication in the patch. I don't have any signs of anxiety, depression, etc. when I have the patch on. Just feel awful when I take it off. I hope you are still visiting this site and will give me insight!
Thanks, SallyBRuss
Helpful - 0
Avatar universal
I have read through so much of this thread and can relate so much!!  But from what I am reading this has all been short term use of the patch. Is there any experience with people who have been on it long term?  I was prescribed this patch back in February of 2013.  It was prescribed to help treat my nausea. Yep it helps, and if only I knew then what just  1 patch could do, I would have never used it. I used it every 3 days for about 5-6 weeks, when I was having surgery to replace a gastric stimulator, which would help ease my nausea enough to make life livable. So we took the patch off right before the surgery. I have never been so sick, If I even moved my eyes within the socket with my eyes shut, I would dry heave and vomit. They put the patch back on, and so much iv Zofran.  Thought it was just from the surgery meds and spinal meds etc. So any time I tried to remove the patch, or forgot to put on after showering etc I would start getting sick within a few hours. By 3-4 hours I can hardly keep my eyes open or hold my head up I am so sick, nauseated, head ache. etc.  I have thought all along it is just my illness nausea.  Wearing the patch does dilate my eyes, blurry vision most of the time. Hard to really focus, especially small print. Last few months the skin behind my ears has been breaking out so bad. The patch adhesive/med just itches horrendously. Skin is broken out, weepy and crusts over. Both ears affected so bad, right now using a steroid cream to to help clear it up. Spoke to my GI who prescribed this med to me nearly a year and a half ago..... We decided it was time to stop the patch. She prescribed IV Zofran, which I could use thru my port. We would do a dose or so of iv Zofran and then remove the patch in the evening. Did that Friday. Just an hour into it my leg began itching horribly, small rash itched bad during night too. Woke a few times during the night, nausea there but not too bad. At 5:25 am my husband gave me 4mg iv Zofran. Helped a bit. by 10 am, I was horrible. Nauseas, couldn't lift my head off the pillow hardly.  Hot and cold, sweating, freezing and head ache. Did another dose iv Zofran at 11:25.  Started vomiting at 11:27. Continued all thru the afternoon. Had to unhook my tpn early, couldn't keep getting up to use the bathroom anymore. Called my infusion company, spoke to my pharmacist about increasing the iv Zofran. She had to call my Dr, or the Dr on call to get an order.  He wouldn't okay it, said that dose should be enough to control it. Advised me to go to the ER. Before starting this, my GI Dr, local pharmacist and infusion company pharmacist have not heard of withdrawal from the scop patch. Nor the arrogant ER DR.  At 6 pm the ER gave me 8 mg IV Zofran. It helped take the vomiting away, but still severe nausea and head ache. Dr comes back in says slap another patch on, that is just a little contact dermatitis.  Wow!  Yes I live in a small town, but wow!  Then asks do I want to be admitted or what.  My husband and I decided to go home and do some more research and yes I slapped another patch on. We were able to increase my iv Zofran to 4 mg every 4 hours.  That helped after 3 hours with the patch on I could lift my head off my pillow for a few minutes.  Still have the patch on, still needing the Zofran.  I am terrified to start over again after having used this patch for so long.  Has anyone used this medication for this long and been successful at coming off?  I totally agree, it should not be FDA approved for anything.... and the first Physician Assistant that prescribed it for me, should not have been able to prescribe it....  Is there any hope for me?
Helpful - 0
Avatar universal
I just used this patch for a 25 hour flight- I had it on for a total of about 40 hours or so, I took it off last night before I went to bed at my destination. I have severe emetophobia (phobia of nausea and vomiting) and I wish I had researched the side effects after removal better before I decided on taking it. It's been about 12 hours since I removed it and I feel fine, but I am absolutely terrified of developing nausea and/or vomiting in a few hours due to withdrawals. That is something that would absolutely traumatize me. In anyone's experience, are the withdrawal symptoms lessened for people who have only used the patch once as opposed to those of you who have taken it many times in a row? I also have tons of meclizine, when should I begin taking that to try and avoid the nausea altogether?
Helpful - 0
1 Comments
wow Im going thru the same thing, I been on the patch 2 months. I have the meclazine and wanna know how to go about it also. I am traumatized behind this patch.
Avatar universal
I wore the patch for 7 days and since taking it off, I have had constant diarrhea, nausea and stomach cramps.  I was dizzy for the first 3-4 days but that passed and now it's been almost two weeks with the other symptoms and no relief.  Has anyone else had this side effect?  I should mention that while on the patch, I had trouble going to the bathroom.  I don't think this could be a virus since it's lasting so long.  Any thoughts?
Helpful - 0
Avatar universal
Put my first patch on last year for a disney cruise..it worked wonders, and after about 26 or so hours of taking it off, I felt slightly off, a little nauseated, like I was coming down with something.  That only lasted for the remainder of that evening.  Fast forward to this past weekend.  Used another patch...took it off Monday morning, felt great until tuesday afternoon.....nausea/dizziness/shortness of breath/fast heartbeat all hit really suddenly.  It was terrible!  Thank God my sister suffers from vertigo and told me to take some bonine because it has meclazine in it.  So i popped two bonine and went to bed (although it took a while for it to kick in).  Today is thursday and I need to keep taking 25mg about every 4 hours, or the dizziness/nausea come right back.  This is terrible!  I will never, ever take this patch again.  I will say out of the five of us who used the patch, I am the only one who got this side effect, go figure!  I am hoping that I will eventually be able to get off the meclazine, as it makes me feel very foggy and slow.  Please, please stay away from the patch!!
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Avatar universal
last night I stupidly put on 2 patches 1 behind each ear,   because I felt a little dizzy... I took them off about 2 hours later because the sight of the patch was itching me....I must have touched my eye with the same fingers that took off the patch on my left ear... about 1/2 hour later my vision was blurred in my left eye.  I was worried of course.. I went to the bathroom mirror and looked at my left eye it was totally dilated.... I hope this is temporary.  As a rule I do not use the patches, I use Meclazine, as needed only.
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