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233488 tn?1310696703

GOOD DIET LOWER RISK OF MACULAR DEGENERATION

NEW JOURNAL STUDIES

High antioxidant intake may lower early AMD risk in genetically predisposed patients
Investigators assessed the intake of antioxidants, zinc, and ω-3 fatty acids in daily foods among 2,167 individuals 55 years or older who were at risk for AMD and enrolled in the Rotterdam Study. Participants completed a semiquantitative food frequency questionnaire at baseline and underwent genetic testing. At about eight years follow-up, they found a possible biological interaction between the CFH Y402H genotype and intakes of zinc, β-carotene, lutein/zeaxanthin, and eicosapentaenoic/docosahexaenoic acid (EPA/DHA), and between the LOC387715 A69S genotype and zinc and EPA/DHA, based on significant synergy indices (P < .05 for all). Archives of Ophthalmology, June 2011

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233488 tn?1310696703
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