I don't relate it to the effexor unless you have narrow angles. You could always try off of it for a while and have pressure re-measured. Sometimes the trabeculectomies just scar over after a while. That is the normal healing phenomenon (the eye natually wants to heal the leak) In fact one of the secrets of successful surgery is to keep the trab from healing too quickly and closing up.
From my review of the internet nad literature, Effexor XR does not usually cause an increase in eye pressure. I would recommend that you seek the care of a glaucoma specialist to assist in fully answering your questions as they pertain to their eyes.
Sandy T. Feldman, M.D., M.S.
ClearView Eye and Laser Medical Center
San Diego, California