I have noticed an increased discomfort of neck muscles and "trouble spots" of my cervical arthritis when our pollen count is up. Pollen is a problem in the area I live. I tend to feel alot of tension muscle discomfort during times of high allergens about. Is the a link to histamine release and muscle discomfort? I also wonder if the humidity plays a role, as the pollen and humidity tend to go hand in hand. I have tried various RX anti-imflamatories with limited results or difficult tolerance and tend to use over the counter aspirin and such. I am wondering if antihistamines would help this literal "pain in the neck"?
There are no consensus trials examining antihistamines in the regulation of pain. I did a little research and found some basic research studies involving mice.
A Japanese study concluded the following:
"Histamine plays an important role in both somatic and visceral pain perceptions through histamine H(1) receptors." (1)
H1 blockers (i.e. antihistamines such as Benadryl) are available over the counter and are safe to try. Again, there is no data suggesting that it works - research is in its early stages - but there are anecdotal reports suggesting efficacy in some patients.
Another consideration would be a referral to a rehabilitiation specialist (physiatrist). They may be able to evaluate the potential for recovery and optimize management of your pain.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
1) Mobarakeh JI, et al. Role of histamine H(1) receptor in pain perception: a study of the receptor gene knockout mice. Eur J Pharmacol 2000 Mar 10;391(1-2):81-9.
Copyright 1994-2018MedHelp.All rights reserved. MedHelp is a division of Vitals Consumer Services, LLC.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.