Aa
MTHFR C677T????
Hey all!!!! I just wanted to ask what this means???? I tested positive for one copy of this, but has anyone else????? and what did they do for you?????
Jacquie
Jacquie
HI,
I HAVE TO COMMENT ON THIS, I AM 43 SOON TO BE 44 YEARS OLD. I HAVE TO VERY BEAUTIFUL DAUGHTERS. I ALSO HAVE 2 TYPES OF MTHFR BOTH OF MINE ARE THE C677T, I NEVER HAD A MISCARRIGE, AND WHEN I HAD MY GIRLS THIS MUTATION WAS NEVER HEARD OF. BUT I WAS A DIABETIC SO I WAS CONSIDERED HIGH RISK, SO I WAS WATCHED CLOSELY FOR THAT. ANYWAY, I WAS GIVEN LOTS AND LOTS OF FOLIC ACID TO TAKE, I TOOK MY PG VITAMINS FAITHFULLY.
MY GIRLS ARE 21 AND 18 NOW, AND THE 21 YEAR OLD JUST GOT MARRIED AND WANTS TO HAVE CHILDREN RIGHT AWAY. I ONLY LEARNED OF MY ILLNESS ABOUT 2 MONTHS AGO, AND WAS TOLD TO HAVE MY GIRLS CHECKED ALSO. THEY BOTH TURNED OUT TO HAVE WHAT I HAVE PLUS THE T1298A FORM, WATCH THEY THINK HAS CAME FROM MY HUSBAND. HE HASN'T BEEN TESTED YET.
MY GIRLS HAVE BEEN TOLD IT WILL PROBABLY BE IMPOSSIBLE TO HAVE CHILDREN. BUT I KNOW WITH THE GOOD LORD ABOVES HELP THEY WILL HAVE BEAUTIFUL CHILDREN. BUT BARE IN MIND ONE THING, THE CHILDREN YOU BRING INTO THE WORLD WILL NO DOUBT CARRY THIS ILLNESS ALSO.
ONE FINAL NOTE, THE ILLNESS CAN EFFECT YOU LATER IN LIFE, WHEN I WAS 36 YEARS OLD, I DEVELOPED BLOOD CLOTS IN MY LUNGS, DUE TO THIS ILLNESS BEING SO SEVERE. I NOW TAKE A DOSE OF 12.5 TO 15 MG OF COUMADIN ADAY, AND CHECK MY BLOOD TWICE A WEEK TO MAKE SURE IT IS THIN ENOUGH, IF NOT I KEEP AND TAKE HERAPIN AT HOME BY SHOT IN MY STOMACHE. I HAVE HAD 3 BLOOD CLOTS HIT MY LUNGS. SO REMEMBER TO TAKE CARE OF YOURSELVES AFTER THE BABIES COME. NEVER SMOKE OR TAKE BIRTH CONTROL OR HORMONES OF ANY TYPE. AND WATCH SURGERIES, AND ALWAYS STAY AS ACTIVE AS POSSIBLE.
I HAVE TO COMMENT ON THIS, I AM 43 SOON TO BE 44 YEARS OLD. I HAVE TO VERY BEAUTIFUL DAUGHTERS. I ALSO HAVE 2 TYPES OF MTHFR BOTH OF MINE ARE THE C677T, I NEVER HAD A MISCARRIGE, AND WHEN I HAD MY GIRLS THIS MUTATION WAS NEVER HEARD OF. BUT I WAS A DIABETIC SO I WAS CONSIDERED HIGH RISK, SO I WAS WATCHED CLOSELY FOR THAT. ANYWAY, I WAS GIVEN LOTS AND LOTS OF FOLIC ACID TO TAKE, I TOOK MY PG VITAMINS FAITHFULLY.
MY GIRLS ARE 21 AND 18 NOW, AND THE 21 YEAR OLD JUST GOT MARRIED AND WANTS TO HAVE CHILDREN RIGHT AWAY. I ONLY LEARNED OF MY ILLNESS ABOUT 2 MONTHS AGO, AND WAS TOLD TO HAVE MY GIRLS CHECKED ALSO. THEY BOTH TURNED OUT TO HAVE WHAT I HAVE PLUS THE T1298A FORM, WATCH THEY THINK HAS CAME FROM MY HUSBAND. HE HASN'T BEEN TESTED YET.
MY GIRLS HAVE BEEN TOLD IT WILL PROBABLY BE IMPOSSIBLE TO HAVE CHILDREN. BUT I KNOW WITH THE GOOD LORD ABOVES HELP THEY WILL HAVE BEAUTIFUL CHILDREN. BUT BARE IN MIND ONE THING, THE CHILDREN YOU BRING INTO THE WORLD WILL NO DOUBT CARRY THIS ILLNESS ALSO.
ONE FINAL NOTE, THE ILLNESS CAN EFFECT YOU LATER IN LIFE, WHEN I WAS 36 YEARS OLD, I DEVELOPED BLOOD CLOTS IN MY LUNGS, DUE TO THIS ILLNESS BEING SO SEVERE. I NOW TAKE A DOSE OF 12.5 TO 15 MG OF COUMADIN ADAY, AND CHECK MY BLOOD TWICE A WEEK TO MAKE SURE IT IS THIN ENOUGH, IF NOT I KEEP AND TAKE HERAPIN AT HOME BY SHOT IN MY STOMACHE. I HAVE HAD 3 BLOOD CLOTS HIT MY LUNGS. SO REMEMBER TO TAKE CARE OF YOURSELVES AFTER THE BABIES COME. NEVER SMOKE OR TAKE BIRTH CONTROL OR HORMONES OF ANY TYPE. AND WATCH SURGERIES, AND ALWAYS STAY AS ACTIVE AS POSSIBLE.
I just tested homozygous for the c677T gene.(two copies of it : ( ) .. after 2 chem pregnancies and 2 miscarriages... i PRAY this is the answer to our problems! I'm now on 5mg of folic acid, b12, b6, baby asprin every day and then heparin before implantation occurs for our next cycle! anyone ever hear of starting heparin before the preg test? I love hearing the success stories it truely gives me hope! i hope this is our answer to why we have had so many losses!! and that there is a treatment!
I am heterozygous for C677T and had a healthy, past due-date, baby boy three years ago - before I knew I carried this gene type. In this past August I miscarried at 14 weeks, though didn't find out until 16 weeks. I am ttc again with no luck so far. My doctor has prescribed Folgard, prenatal vits, and baby aspirin. I had two regular cycles, 1 late cycle, 1 early cycle, and have been spotting for the last 8 days even though my period wasn't due for two weeks. So, I'm frustrated, but not beaten. I've had a healthy baby - I know it's possible. So I want you all to be hopeful. I feel for all of you and am very sorry for your losses.
Hi mthfrhetero,
I am so sorry that you have had 6 m/c's.
I did want to encourage you and anyone else who has compound heterozygous MTHFR. It is definitely possible to have healthy babies. I don't understand it, but I was able to have 3 healthy pregnancies. Then I had 2 miscarriages in a row. That is how I found out that I had the MTHFR mutation. Right now, I am researching it and trying to find a doctor who understands what the heck it is. It seems just as luvmybaby121 said that doctors don't really know what it is. Some get defensive because I seem to have more knowledge about it than them. Others aren't so proud and come out and say that they don't know much about it. Others fake it... but I can tell. It is kind of scary.
My ob doctor who I was seeing me when I had the m/c's does not seem to agree with me that compound hetero MTHFR could cause miscarriage or increased homoscysteine levels. So, I need a new doctor. I bypassed her and went to my family physician who did not really know much, but let me get the homocysteine test and a host of other tests that might be relevant. Then he put me on baby aspirin, folic acid 1 mg, generic folgard (folic acid, B12 & B6) and my prenatal vitamin. So, I meet with him on Monday to go over some lab work (homocysteine levels, B6 and B12, thyroid etc...). I feel like he is on the right track, but definitely not an expert. I am kind of guiding him along and telling him what I need to take and test for.
My mother-n-law went on a cruise with her best friend who happens to be a high risk ob doc. So, I asked her to "consult her about my problem" while basking on the beach. I can't wait to here what she has to say. I will talk to her on Monday also. I also have a friend who works in research and she has been gathering lots of articles about mthfr and helping me get as educated as possible (I will share some of those findings later.). She is also meeting with other scientist/professors that work with homocysteine research.
Then...I consulted with my children's pediatrician (since my children have 50% chance of having this mutation) and he referred us to a pediatric geneticists. Can't wait to see what he has to say.
Today, I got back on line to copy down some of the things people's doctors have been giving them so that I can figure out what to do next.
So, I am trying my best to do everything I can to help myself have a healthier pregnancy (if we decide to try again). It makes me very sad to hear all of all of the women who have had miscarriages or stillbirths because of this problem. I am so very thankful that I have my 3 boys. We were trying for our little girl.
I am so sorry that you have had 6 m/c's.
I did want to encourage you and anyone else who has compound heterozygous MTHFR. It is definitely possible to have healthy babies. I don't understand it, but I was able to have 3 healthy pregnancies. Then I had 2 miscarriages in a row. That is how I found out that I had the MTHFR mutation. Right now, I am researching it and trying to find a doctor who understands what the heck it is. It seems just as luvmybaby121 said that doctors don't really know what it is. Some get defensive because I seem to have more knowledge about it than them. Others aren't so proud and come out and say that they don't know much about it. Others fake it... but I can tell. It is kind of scary.
My ob doctor who I was seeing me when I had the m/c's does not seem to agree with me that compound hetero MTHFR could cause miscarriage or increased homoscysteine levels. So, I need a new doctor. I bypassed her and went to my family physician who did not really know much, but let me get the homocysteine test and a host of other tests that might be relevant. Then he put me on baby aspirin, folic acid 1 mg, generic folgard (folic acid, B12 & B6) and my prenatal vitamin. So, I meet with him on Monday to go over some lab work (homocysteine levels, B6 and B12, thyroid etc...). I feel like he is on the right track, but definitely not an expert. I am kind of guiding him along and telling him what I need to take and test for.
My mother-n-law went on a cruise with her best friend who happens to be a high risk ob doc. So, I asked her to "consult her about my problem" while basking on the beach. I can't wait to here what she has to say. I will talk to her on Monday also. I also have a friend who works in research and she has been gathering lots of articles about mthfr and helping me get as educated as possible (I will share some of those findings later.). She is also meeting with other scientist/professors that work with homocysteine research.
Then...I consulted with my children's pediatrician (since my children have 50% chance of having this mutation) and he referred us to a pediatric geneticists. Can't wait to see what he has to say.
Today, I got back on line to copy down some of the things people's doctors have been giving them so that I can figure out what to do next.
So, I am trying my best to do everything I can to help myself have a healthier pregnancy (if we decide to try again). It makes me very sad to hear all of all of the women who have had miscarriages or stillbirths because of this problem. I am so very thankful that I have my 3 boys. We were trying for our little girl.
Hi All,
I am new to this forum, sailing in the same boat - 6 m/cs - having MTHFR compound heterozygous. Tried lovenox, baby aspirin, progesterone. None of my OB/REI/Perinatologist suggested taking high folic acid. I am really excited to see baby1234's progress. I am interested in hearing experiences on people with similar MTHFR comp.hetero who have gone thru full term.
Good luck to you all. baby1234, please keep us posted with your progess. I am really motivated looking at this forum, even though I am not depressed, doing good...positive attitude..not my fault for being born with MTHFR! Cheer up, let's try our best and enjoy with what we are/have too!
Have a great day.
I am new to this forum, sailing in the same boat - 6 m/cs - having MTHFR compound heterozygous. Tried lovenox, baby aspirin, progesterone. None of my OB/REI/Perinatologist suggested taking high folic acid. I am really excited to see baby1234's progress. I am interested in hearing experiences on people with similar MTHFR comp.hetero who have gone thru full term.
Good luck to you all. baby1234, please keep us posted with your progess. I am really motivated looking at this forum, even though I am not depressed, doing good...positive attitude..not my fault for being born with MTHFR! Cheer up, let's try our best and enjoy with what we are/have too!
Have a great day.
Have an Answer?
You are reading content posted in the Fertility and Trying to Conceive Community
Many couples are turning to acupuncture to treat infertility. But does it work? We take a closer look.
Does exercise really lower fertility? We take a look at 8 common myths about fertility.
Your guide to safely exercising throughout your 40 weeks.
Learn which foods aren't safe to eat when you're eating for two.
Is your biological clock sounding the alarm? Dr. Elaine Brown explains new advances in egg freezing.
A list of national and international resources and hotlines to help connect you to needed health and medical services.
