Aa
My Update
Hello ladies,
How is everyone doing? I’m great.
Some of you might of read my story, if not I’ll give you a brief of it.
I’m a healthy 26yr old, that had two fail ivfs my husband I are getting ready to start our third ivf, I had both of my tubes remove, they were so very damage. I read that by having your tubes remove, if they are completely damage might increase our chances at ivf? I’m healthy and I respond very well to the medicine, and my embryos are always prefect.I’m young. I don’t drink nor smoke, and I'm not over weight. I only weight 125 really don’t know y it’s not working? My oavries are great and my uterus is great as well. Sometimes I get sharp pain in my vagina, my dr says it might be scar tissue . My Dr say that I'm good to go. I got pregnant last year, but it ended up a tubal and that was my 1st ever to get pregnant. I just got my tubes removed in June.
Here is my update. I’m schedule to start my Menopur and Follistim this Saturday, but I call my Dr this morning to let him know that I’m going to cancel this cycle. I left the message with his nurse and Receptionist, so I haven’t heard back from him yet. The reason why I’m canceling this cycle is because yesterday I went to another Dr and He went over my medical records and he stated that my uterine ling should be 9mm instead of 8.8 and he told me by taking Viagra would thicken my lining by 70%.
Also he stated that my husband should have this test done on his Sperm DNA, that could be affecting my embryos. The initial for this test is call SDI, it’s new and they don’t accept insurance for this test, which is $270.00. Also he told me I should get Immune check to see if I have this. This test isn’t cover by insurance either. It’s like @270.00 also. This test is to see if my body is attacking the embryos. He told me that my husband and I should get these two test done before attempting anymore IVF’s. He also said everything else looks great.
When I told my husband about the news yesterday he got all mad and said, look we have been to two Drs already and they all said that it was your tubes that was causing the problem. He got all upset and said that he didn’t want to cancel this cycle. The reason why he didn’t want to cancel this cycle is because we are paying $420.00 a mth for this health insurance, so I told him would you rather pay $420.00 for health insurance instead of trying to come up with $10,000? Also we have had the same Dr for almost a year and had two failed IVF’s with this Dr and I don’t want it to be our third. Also each time we had both failed IVF’s my Dr say’s he don’t know what could be wrong and ever checks me for anything. I just want to make sure I have everything check before jumping into a third one. We have two more trys with our insurance before we run out of insurance funds and I just want to make sure everything is check. I really trust this Dr that I saw yesterday and I went to one of his seminar and he is a good Dr.
So when I put all my facts in info together my husband agrees to wait and take these test and go with the new Dr.
Sorry to have such a long story.
Please keep us in your prayers.
How is everyone doing? I’m great.
Some of you might of read my story, if not I’ll give you a brief of it.
I’m a healthy 26yr old, that had two fail ivfs my husband I are getting ready to start our third ivf, I had both of my tubes remove, they were so very damage. I read that by having your tubes remove, if they are completely damage might increase our chances at ivf? I’m healthy and I respond very well to the medicine, and my embryos are always prefect.I’m young. I don’t drink nor smoke, and I'm not over weight. I only weight 125 really don’t know y it’s not working? My oavries are great and my uterus is great as well. Sometimes I get sharp pain in my vagina, my dr says it might be scar tissue . My Dr say that I'm good to go. I got pregnant last year, but it ended up a tubal and that was my 1st ever to get pregnant. I just got my tubes removed in June.
Here is my update. I’m schedule to start my Menopur and Follistim this Saturday, but I call my Dr this morning to let him know that I’m going to cancel this cycle. I left the message with his nurse and Receptionist, so I haven’t heard back from him yet. The reason why I’m canceling this cycle is because yesterday I went to another Dr and He went over my medical records and he stated that my uterine ling should be 9mm instead of 8.8 and he told me by taking Viagra would thicken my lining by 70%.
Also he stated that my husband should have this test done on his Sperm DNA, that could be affecting my embryos. The initial for this test is call SDI, it’s new and they don’t accept insurance for this test, which is $270.00. Also he told me I should get Immune check to see if I have this. This test isn’t cover by insurance either. It’s like @270.00 also. This test is to see if my body is attacking the embryos. He told me that my husband and I should get these two test done before attempting anymore IVF’s. He also said everything else looks great.
When I told my husband about the news yesterday he got all mad and said, look we have been to two Drs already and they all said that it was your tubes that was causing the problem. He got all upset and said that he didn’t want to cancel this cycle. The reason why he didn’t want to cancel this cycle is because we are paying $420.00 a mth for this health insurance, so I told him would you rather pay $420.00 for health insurance instead of trying to come up with $10,000? Also we have had the same Dr for almost a year and had two failed IVF’s with this Dr and I don’t want it to be our third. Also each time we had both failed IVF’s my Dr say’s he don’t know what could be wrong and ever checks me for anything. I just want to make sure I have everything check before jumping into a third one. We have two more trys with our insurance before we run out of insurance funds and I just want to make sure everything is check. I really trust this Dr that I saw yesterday and I went to one of his seminar and he is a good Dr.
So when I put all my facts in info together my husband agrees to wait and take these test and go with the new Dr.
Sorry to have such a long story.
Please keep us in your prayers.
The SDIa test is a fantastic one. It basically tells you what chances you have of your DH sperm being able to fertilize your egg. Another great immunological test is for natural killer cells. This test will tell you if there are factors in your body attacking the embryo. If you go see a good RE who is knowledgable in immunological reasons for infertility doors may SWING open that you never knew were there. I am an embryologist and completely agree that there are TONS of reasons for failed IVF besides embryo quality. GL 2 u!!
I'm very happy for you and I'll keep praying for you. Yea he is very nice. He really seem like he really cared about me and about me getting pregnant. My husband said that all Drs do that, so they can get your money, but he seem so different. I really thought about this whole ordeal last night and prayed to God and cried.I'm going to switch to him. My husband didn't want to, because he is finally comfortable with our Dr that we have now, but I told him we have to try someone different and stop playing around. I'm kinda happy that I cancel this cycle, because I miss working out and I gain a little weight I'm now like 130 I use to be 125 only five pounds I gain, but I just miss my old life, like working out playing softball and my body needed a break from all the shots and medications. I think my husband is just tired of paying this $420.00 a month for insurance and his insurance on his job isn’t as good as the one that I have. I tell him, we are very blessed to have this insurance, because some people don’t even have insurance that covers this. He gets the point now and he agrees.Well I wish you much luck and stay in touch.
No, we haven't had to do IVF yet...I get pregnant very easy on my own..this is my 4th pregnancy in 10 months...I've just never made it past 8 weeks before...We shall see how this one progresses. No, I'm in Arizona yet I did have a phone consult with Dr. Saleh...He is so nice.
Keis, I am going to ask my RE about that for my next round! Thanks for the info
I am also grateful for you telling us about that website.......it's very informative!!!! Thanks!
I am also grateful for you telling us about that website.......it's very informative!!!! Thanks!
You are so welcome. I hope we all have babies soon, this time I'm going really take my time before I just jump into my third ivf.
oh i've had a phone consult with Dr. Saleh...he's great...I actually did the NK Killer Cells test and mine came back abnormal...I've also had 3 miscarriages...I'm pregnant right now and if this one doesn't stick, then I'm going to look into doing the treatment for the NK Killer Cells.
Thanks for posting that site I'd never heard of that before but if I don't get some answers soon from my Dr. I may see if she will refer me to the St. Louis facility that's less than 3 hours from me.
Good luck to your tests... hopefully they may find something that is causing this failures..so next time it will sticks...let us know the outcome of this also...
Read this, it's just a short info and then go to the website and read the rest. it's www.haveababy.com and let me know what you think.
The high incidence of unpleasant side effects associated with nitroglycerine therapy (e.g. severe headaches, nausea, and light-headedness brought about by fluctuations in blood pressure) resulted in poor patient tolerance. Accordingly, when Sildenafil (Viagra) was shown to facilitate penile erection through increasing penile blood flow, without eliciting bothersome side effects, we decided to investigate whether this drug could replace nitroglycerine for the improvement of endometrial development. This time, with ready access to UCFD, we set out to examine for a cause and effect relationship between Viagra-induced enhancement of uterine blood flow and improved endometrial growth in women with poor endometrial development.
We elected to incorporate Viagra into vaginal suppositories in an attempt to improve local uterine absorption and minimize the incidence of systemic side effects .To this end, we enlisted the services of a compound pharmacist and began testing the effect of vaginally administered Viagra on uterine blood flow and on estrogen-induced endometrial development. Four women with chronic histories of poor endometrial development and failure to conceive following several advanced fertility treatments were evaluated for a period of 4-6 weeks and then underwent IVF with concomitant Viagra therapy. Viagra vaginal suppositories were administered four times daily for 8-11 days and were discontinued 5-7 days prior to embryo transfer in all cases.
We reported on our findings in a preliminary study, published in the prestigious journal, “Human Reproduction” (April 2000). The findings clearly demonstrated that vaginal Viagra produced a rapid and profound improvement in uterine blood flow and that this was followed by enhanced endometrial development in all four cases. While three of the four women subsequently conceived, the study is too small to prove that these pregnancies can be attributed to the Viagra therapy. Larger independent and controlled studies will be needed to demonstrate this.
The high incidence of unpleasant side effects associated with nitroglycerine therapy (e.g. severe headaches, nausea, and light-headedness brought about by fluctuations in blood pressure) resulted in poor patient tolerance. Accordingly, when Sildenafil (Viagra) was shown to facilitate penile erection through increasing penile blood flow, without eliciting bothersome side effects, we decided to investigate whether this drug could replace nitroglycerine for the improvement of endometrial development. This time, with ready access to UCFD, we set out to examine for a cause and effect relationship between Viagra-induced enhancement of uterine blood flow and improved endometrial growth in women with poor endometrial development.
We elected to incorporate Viagra into vaginal suppositories in an attempt to improve local uterine absorption and minimize the incidence of systemic side effects .To this end, we enlisted the services of a compound pharmacist and began testing the effect of vaginally administered Viagra on uterine blood flow and on estrogen-induced endometrial development. Four women with chronic histories of poor endometrial development and failure to conceive following several advanced fertility treatments were evaluated for a period of 4-6 weeks and then underwent IVF with concomitant Viagra therapy. Viagra vaginal suppositories were administered four times daily for 8-11 days and were discontinued 5-7 days prior to embryo transfer in all cases.
We reported on our findings in a preliminary study, published in the prestigious journal, “Human Reproduction” (April 2000). The findings clearly demonstrated that vaginal Viagra produced a rapid and profound improvement in uterine blood flow and that this was followed by enhanced endometrial development in all four cases. While three of the four women subsequently conceived, the study is too small to prove that these pregnancies can be attributed to the Viagra therapy. Larger independent and controlled studies will be needed to demonstrate this.
Good luck with your new doctor. It sounds like you are on the right track. I hope these new tests shed some light on the situation. I absolutely think it is a good idea to check these other issues befoe you move on to another IVF. I'll keep you in my prayers.
Hey girl, it's ok the insurance is call Definity Health & UnitedHeathlcare they merged together. I really like it I never have any co pays and it pays for all of my meds under my med coverage, and not towrds Fertility.It is a blessing to have this insurance. I thank God everyday, because without it we wouldn't be able to do this. I'm pay cobra I got this ins from my old job and I'm not there anymore, so that is why we are paying $420.00.
Are the tests anti sperm anti body tests? When they take his sperm and your blood and see how they react together? I had this done and ended up my blood was fine with DH's sperm. This test is worth doing. Good luck with your new doctor. Viagra...hmmmm. Let us know how it works for you!
All they do is take your blood and send it to the lab and and you'll get your results in like two or three days. I didn't send th second half, it's to long and you can go to their web and it has everything, hope it's some help to you.
Please go check out their websit and see how many women went through 2,3,4,5,6,7,8,9,10, times before going to see this Dr and got pregment right after seeing him and had embryo left over. it's call www.haveababy.com Let me known what you think.
Immune Implantation Failure: A Rational Basis for Treatment
Immunologic Implantation Failure:
A Rational Basis for Treatment.
Currently, with few exceptions, practitioners of Assisted Reproduction tend to attribute “unexplained and/or repeated” IVF failure(s), almost exclusively to poor embryo quality, advocating adjusted protocols for ovarian stimulation and/or gamete and embryo preparation as a potential remedy. The idea that having failed IVF, all that it takes to ultimately succeed is to keep trying over and over using the same recipe is over simplistic. There are numerous non-embryologic that can be responsible for failed IVF. This presentation addresses immunologic factors that cause implantation failure:
The implantation process begins six or seven days after fertilization of the egg. At this time, specialized embryonic cells (i.e., trophoblast), which later becomes the placenta, begin growing into the uterine lining. When the trophoblast and the uterine lining meet, they, along with Immune cells in the lining, become involved in a "cross talk" through mutual exchange of hormone-like substances called cytokines. Because of this complex immunologic interplay, the uterus is able to foster the embryo’s successful growth. Thus, from the earliest stage, the trophoblast establishes the very foundation for the nutritional, hormonal and respiratory interchange between mother and baby. In this manner, the interactive process of implantation is not only central to survival in early pregnancy but also to the quality of life after birth.
Considering its importance, it is not surprising that failure of proper function of this immunologic interaction during implantation has been implicated as a cause of recurrent miscarriage, late pregnancy fetal loss, IVF failure, and infertility. A partial list of immunologic factors that may be involved in these situations includes anti-phospholipid antibodies (APA), antithyroid antibodies (ATA), and, perhaps most importantly, activated natural killer cells (NKa). Presently, these immunologic markers can be adequately measured by only a few (less than a half dozen) highly specialized reproductive immunology laboratories in the United States, from patient blood samples.
1) Antiphospholipid Antibodies (APA)
A large body of literature has confirmed that patients who experience repeat IVF failures often have increased levels of circulating APAs. Compelling evidence has also demonstrated that up to 50% of women with pelvic endometriosis and unexplained infertility harbor APAs in their blood. Despite this information, the role of APAs in reproductive outcome is still controversial. In 1995, we proposed that in cases of non-male factor infertility, women who test positive for APAs be treated with a mini-dose heparin and low-dose aspirin to improve IVF implantation and thus birth rates. This approach was based upon research that suggested that heparin repels APAs from the surface of trophoblast cells, thus enhancing their development and aspirin, by inhibiting platelets from adhering to the early trophoblast, might prevent clot formation in the early uteroplacental vasculature. We subsequently demonstrated that heparin/aspirin therapy improved IVF outcome only for women whose APA testing was positive for antibodies other than those directed against two specific phospholipids, i.e., phosphatidylethanolamine (PE) and phosphatidylserine (PS), and that only women who had IgG/IgM-related anti-PE or anti-PS antibodies experienced a significant improvement in IVF implantation and birth rates when IVIg therapy, instead of heparin/aspirin, was initiated more than 1 week prior to embryo transfer.
Our recent observations suggest that the use of heparin alone is just as effective as combining it with aspirin. Accordingly we no longer prescribe aspirin at all. Notwithstanding the above, the following recent observations suggest that APAs rather than being causally linked to implantation failure, might serve to identify a population at inordinate risk of implantation failure and that NKa, through the unregulated release of embryotoxins, are in fact the real culprits.
Immune Implantation Failure: A Rational Basis for Treatment
Immunologic Implantation Failure:
A Rational Basis for Treatment.
Currently, with few exceptions, practitioners of Assisted Reproduction tend to attribute “unexplained and/or repeated” IVF failure(s), almost exclusively to poor embryo quality, advocating adjusted protocols for ovarian stimulation and/or gamete and embryo preparation as a potential remedy. The idea that having failed IVF, all that it takes to ultimately succeed is to keep trying over and over using the same recipe is over simplistic. There are numerous non-embryologic that can be responsible for failed IVF. This presentation addresses immunologic factors that cause implantation failure:
The implantation process begins six or seven days after fertilization of the egg. At this time, specialized embryonic cells (i.e., trophoblast), which later becomes the placenta, begin growing into the uterine lining. When the trophoblast and the uterine lining meet, they, along with Immune cells in the lining, become involved in a "cross talk" through mutual exchange of hormone-like substances called cytokines. Because of this complex immunologic interplay, the uterus is able to foster the embryo’s successful growth. Thus, from the earliest stage, the trophoblast establishes the very foundation for the nutritional, hormonal and respiratory interchange between mother and baby. In this manner, the interactive process of implantation is not only central to survival in early pregnancy but also to the quality of life after birth.
Considering its importance, it is not surprising that failure of proper function of this immunologic interaction during implantation has been implicated as a cause of recurrent miscarriage, late pregnancy fetal loss, IVF failure, and infertility. A partial list of immunologic factors that may be involved in these situations includes anti-phospholipid antibodies (APA), antithyroid antibodies (ATA), and, perhaps most importantly, activated natural killer cells (NKa). Presently, these immunologic markers can be adequately measured by only a few (less than a half dozen) highly specialized reproductive immunology laboratories in the United States, from patient blood samples.
1) Antiphospholipid Antibodies (APA)
A large body of literature has confirmed that patients who experience repeat IVF failures often have increased levels of circulating APAs. Compelling evidence has also demonstrated that up to 50% of women with pelvic endometriosis and unexplained infertility harbor APAs in their blood. Despite this information, the role of APAs in reproductive outcome is still controversial. In 1995, we proposed that in cases of non-male factor infertility, women who test positive for APAs be treated with a mini-dose heparin and low-dose aspirin to improve IVF implantation and thus birth rates. This approach was based upon research that suggested that heparin repels APAs from the surface of trophoblast cells, thus enhancing their development and aspirin, by inhibiting platelets from adhering to the early trophoblast, might prevent clot formation in the early uteroplacental vasculature. We subsequently demonstrated that heparin/aspirin therapy improved IVF outcome only for women whose APA testing was positive for antibodies other than those directed against two specific phospholipids, i.e., phosphatidylethanolamine (PE) and phosphatidylserine (PS), and that only women who had IgG/IgM-related anti-PE or anti-PS antibodies experienced a significant improvement in IVF implantation and birth rates when IVIg therapy, instead of heparin/aspirin, was initiated more than 1 week prior to embryo transfer.
Our recent observations suggest that the use of heparin alone is just as effective as combining it with aspirin. Accordingly we no longer prescribe aspirin at all. Notwithstanding the above, the following recent observations suggest that APAs rather than being causally linked to implantation failure, might serve to identify a population at inordinate risk of implantation failure and that NKa, through the unregulated release of embryotoxins, are in fact the real culprits.
MY PRAYER WILL BE WITH YOU TO THE END! I KNOW THE STRESS YOU & DH ARE GOING THROUGH. I HAVE ONE QUESTION THATS HAS NOTHING TO DO WITH IVF.MY INSURANCE DOES NOT COVER ANYTHING WITH FERTILITY & I WAS WONMDERING WHAT TYPE OF INSURANCE YOU & DH HAVE??? SORRY TO BE SOO INTO YOUR BUSINESS BUT IM THINKING OF CHANGING INSURANCE BUT WANTED ONE THAT COVERS FERTILITY.
GOOD LUCK!!!WILL PRAYING FOR YOUR BFP!
GOOD LUCK!!!WILL PRAYING FOR YOUR BFP!
Have an Answer?
You are reading content posted in the Fertility and Trying to Conceive Community
Many couples are turning to acupuncture to treat infertility. But does it work? We take a closer look.
Does exercise really lower fertility? We take a look at 8 common myths about fertility.
Your guide to safely exercising throughout your 40 weeks.
Learn which foods aren't safe to eat when you're eating for two.
Is your biological clock sounding the alarm? Dr. Elaine Brown explains new advances in egg freezing.
A list of national and international resources and hotlines to help connect you to needed health and medical services.
