Ok, I'm a 19 year old woman who has been diaganosed with PCOS by my gynecologist. What I need to know about is a few things actually. He prescribed me with Prometrium 200mgs, once a day at bedtime. Ok, so I took the pills, twelve days...on the second day I began to bleed...It just seemed to come and come...and lasted for about five days. I did not ovulate during this time. Ever since I was finished with it, I have had the cramps, only worse than it's supposed to be, and it's a constant pain, I called the office, and they told me that I did not have a period, that the meds didn't work this round... they said that those five days were "spotting". Ok, so yesterday, they started me on Prometrium again, only this time its 400mgs a day at bedtime...the cramps that got worse after the first time are at a stead 7 on pain wise on a scale of 1-10. I took Midol, thinking it would be safe for it, but it is just hurting at the same amount of pain. I'm not allergic to the meds, it's just painful. I've been doing a lot of research about the PCOS and about Prometrium, and things for me don't look too positive. I'm seriously thinking about a hystorectomy, but I'm worried, and Im scared, I don't know what to do, and I've looked up everything, or at least what seems to be everything about PCOS, because now all I'm getting is repeated info that I've already found...What am I supposed to do...I want kids someday, but the meds aren't working, and I'm in pain. Anyone else have this kind of problem? oh, and I'm supposedly pre diabetic because I'm obese...I never used to be, I stoped having periods two years ago, and I used to weigh 160, but now I weigh somewhere around 260. That's one hundred pounds that I gained outta no where, and I've done all sorts of things to loose it...and my gynecologist says that I got PCOS because of my own problem of gaining the weight...I'm just so hurt and confused...I used to have really bad depression spells, and I'm a major depression person, just not diagnosed, and I'm so sad that I don't even know what to do, I've tried to loose the weight....but I can't, I've tried almost everything, my fasting blood sugar was like 200, but diabetes, type two runs in the family anyway, but still...How can I loose weight if I cant loose it? I eat healty, I exercise a lot, but I still weigh 260. What can I do???