As with all medications in pregnancy, they are best avoided unless the benefits outweigh the risks. There is not much data available on Seroquel, but what is available suggests that if you can find a safer alternative you would be better off. If you need your medication to be healthy and there aren't any available alternatives, then ( just like people who have seizure disorders) it may be necessary to take the risk.
I know this sounds like a wishy washy answer, and it is! Bottom line, best to stop it when you get pregnant IF possible.
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