i dont know whether you received my first comment but to answer your question about matrine and oxymatrine i hqave taken them in the form of the chinese herb kushen while waiting for dr chias new product to come out. i think that it is working for me and without any sideaffects. dr chia has been nice enough to communicate with me for over ayear via email . being a veterinarian i have a lot of medical knowledge which has allowed me to investigate many many causes and treatment for chronic diseases. i have a tremendous amount of confidence in dr chias knowledge and sincerity. however his emphasis is on enterovirus as a cause of many chronic fatigue syndromes. some patients may have other causes thereby making his therapy unsuccessful. however my endless hours looking for answers for myself has told me that somewhere there is an answer for everyone.