I was taking Prilosec OTC 'til it started making me really nauseous every time I took it. A friend of mine warned me not to take Prilosec, because it ruined the lining of her stomach and her intestines. Since the medication was making me feel sick all the time, I stopped taking it when she told me this.
Another friend of mine told me about the link between food sensitivities and GERD. I tested her theory and found it to be true. Certain foods that you wouldn't think would be associated with aggravating GERD do, in fact, aggravate my own GERD. Ginger is actually one of them. It also raises my heart rate. Not Tachycardia, but still rapid heart rate. If I still have breakthrough heartburn or reflux or ate something that I didn't expect to cause problems, I take prescription strength Benadryl. Guess what, it works! So, I know that what my friend told me about food sensitivities and GERD is true, especially for those of us who already have other allergies.
I don't know of any GERD medications that don't block absorption or mess with the lining of the stomach and intestines.
Try avoiding the foods that we're always told to avoid. Try an elimination diet, too. You may not be aware of this, but sulfites bother some people. Sulfites aggravate my GERD. Sulfites are in all processed foods. There are ways of eating the foods you like, without having to spend your life in the kitchen. Old fashioned crock pots are coming back into fashion and are great for busy families, too. I don't have any food in my place that is canned, except the cat's food, and I don't have any packaged prepared foods. I also don't have any foods with gluten in them. Anything in the freezer is either meat, or it's something I made from scratch. While avoiding sulfites, avoid white sugar and high fructose corn syrup. These contain huge amounts of sulfites. Cane sugar and raw sugar are safe and don't contain sulfites. I also avoid honey, because I discovered that I'm allergic to honey, too.