I have chronic pancreatitis (not alcohol related). My pancreatitis is due to a lot of ERCP's, sphincterotomies and stents that have caused scarring in my duct and in the head of my pancreas. My amylase usually runs between 200 - 500. Recently it has been at 967. My lipase is 302. I feel the same, which is not great. I have a lot of pain and take norco to alleviate it. I haven't ate anything different or done anything out of the ordinary. I am really tired. I am nursing a 4 month old baby (first child, yeah!!!). Should I be concerned about the sudden jump? My doctor seemed a little worried. Everything I read says that having a amylase that high causes irreversible damage and/or cancer and sometimes death. I was in and out of the hospital the first time I was ill, but do not want to go now. Should I? I don't know what to do.