Aa
A
A
A
Close
Gastroenterology Community
31.5k Members
Avatar universal

High Amylase and Lipase (5x's) No Diagnosis

I also need a “red herring” explanation please. With Amylase and Lipase both over 5 times normal, gas, continual deep pain in upper right quadrant, fatigue and nausea, I'm at square one in getting any answers. Tests since Dec 2015: CT, Colonoscopy, Endoscopy, MRCP, Celiac blood test - all "appear normal". Primary Care Doc says "Nothing more to do. Everything looks fine". But when the Gastroenterologist gave me the "fish theory" it sounded like he thinks it's all a figment of my imagination. I don't smoke or drink and control diabetes with diet, exercise and minimum dose of Metformin ER. Fats are very problematic. I need some hope and direction! Any comments appreciated. It is good to hear I am not alone although I do not wish this on anyone. Does anyone have any suggestions or comments?
1 Responses
1530171 tn?1448133193
It sounds like a typical case of cholecystitis, however pancreatitis has to be ruled out as well.
These are  2 conditions where both  Amylase and Lipase levels are elevated, however, cholecystitis affects the  upper right quadrant.
The lack of a diagnosis, should this suspicion prove to be correct, puzzles me, as it is rather common and simple to diagnose. I guess, there's always the possibility of missing what seems to be the obvious to most doctors.
If your gastroenterologist is not willing to be supportive and work with you, perhaps, seeking a 2nd opinion would be the logical next step. Ask for a HIDA scan which has high sensitivity, if the ultrasound does not help in establishing a diagnosis.
BTW, diabetes is a  risk factor in both cholecystitis and pancreatitis.
Best wishes,
Niko
Have an Answer?
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Learn which OTC medications can help relieve your digestive troubles.
Is a gluten-free diet right for you?
Discover common causes of and remedies for heartburn.
This common yet mysterious bowel condition plagues millions of Americans
Don't get burned again. Banish nighttime heartburn with these quick tips
Get answers to your top questions about this pervasive digestive problem