I am trying to find out if it is safe to take Nexium and Zantac together. I also take Xanax 1mg. I have GERDS and Barrett's Esophogus. I don't have indigestion, because I am taking the NEXIUM 40mg. , I was wondering if it is safe to take Zantac 75mg. with it. I have been getting these little pinpoint pimple like things in my mouth and on the roof of my mouth, sides, and the back of my tongue. My doctor said it might be my stomach causing these little pimples, but he never answered me. Does anyone have any answers ? Please Help. These little pimples feel like sandpaper in my throat and are driving me nuts !