About two weeks into my new Wellbutrin regimen (150 mg. SR added to my nightly dose of 33 mg. Remeron), I developed a pretty intense bout of heartburn. This heartburn has stayed with for most of the entire past week-and-a-half, and I've recently added a daily Prilosec to my cocktail, which clears up the problem almost entirely. I'm getting ready to bump my dose up to a second WB 150 SR daily, and am worried about this heartburn issue, as I seem to really be responding to this drug. Has anyone else experienced heartburn with Wellbutrin, and if so how did you treat it and did it eventually go away? I'm wondering if a switch from SR to XL is indicated in order to slow the release of the drug to potentially help with my stomach issues.