if you eat half popped or un-popped kernels it can. especially if your one of those people who don't digest corn well, at that point its kind of like swallowing fine gravel or kitty litter. My hubby doesn't eat popcorn for this very reason.
Popcorn is high in fiber, thus cleans the walls of the intestines, which is a good thing usually. In some cases, it is NOT a good thing. If you have an inflammatory bowel disease high fiber foods can further irritate the intestinal lining causing pain, bleeding, etc.