Why am I so tired? Why do I keep forgetting everything?

[IMON22S]

I am so tired of being tired all the time. It doesn't matter how much sleep I get, I normally sleep 8 hours but there are days in the week i sleep up to 16. I never feel fully rested. I am a 26 year old male. My short term memory is completely shot, if you tell me something then ask 5 to 15 mins later I'll forget at least half. I have to write lists for everything, taking allergy medication, cleaning dishes, showering, walking the dog, and working. I live a pretty much stress free life, I only work 2 - 3 days a week.
Sometimes I also have trouble describing things, this morning I was talking to my about what we ate yesterday and I told her we ate a morning taco instead of a breakfast taco. This has been going on for as long as i can remember  just lately it has been getting worse. I take ADD medication adderall in the morning, i figured this was causing the issue so i stopped taking it for about a month or 2. My tiredness didn't get any better, slightly worse for the first week off the meds. I had a sleep study done no sleep apnea, higher than normal dela wave sleep, REM was a little delayed but i didn't get much sleep the night before.  
Now just in case people ask I weigh 300lbs and I am 5'10". About a year and a half ago I weighed 210 and I was only slightly more awake I'm talking 2% to 4%. I can completely understand that my weight has something to do with this, but there is no way in the world does it explain this level of fatigue.
I had some blood work done in Jan. 7,2015

Cholesterol, total 159 mg/dL
Triglycerides 55 mg/dL
HDL Cholesterol 54 mg/dL
VLDL  Cholesterol 11 mg/dL
LDL  Cholesterol 94 mg/dL

WBC 9.8 x10E3/uL
RBC 4.76 x10E3/uL
Hemoglobin 15.4 g/dL
Hematocrit 44.9 %
MCV 94 fL
MCH 32.4 pg
MCHC 34.3 g/dL
RDW 13.7 %
Platlets 266 x10E3/uL
Neutrophils 64 %
Lymphs 25 %
Monocytes 8 %
Eos 3 %
Basos 0 %
Immature Cells NP
Neutrophils(absolute) 6.2 x10E3/uL
Lymphs(absolute) 2.5 x10E3/uL
Monocytes(absolute) 0.8 x10E3/uL
Eos(absolute) 0.3 x10E3/uL
Basos(absolute) 0.0 x10E3/uL
Immature Granulocytes 0 %
Immature Grans (abs) 0.0 x10E3/uL
NRBC NP
Hematology Comments NP

Glucose, Serum 104 mg/dL
BUN 10 mg/dL
Creatinine, Serum .078 mg/dL
eGFR If nonAfticnAm 125 mL/min/1.73
BUN/Creatinine Ratio  13
Sodium, Serum 139 mmol/L
Potassium,  Serum 4.7 mmol/L
Chloride,  Serum 100 mmol/L
Carbin Dioxide, Serum 26 mmol/L
Calcium,  Serum 9.3 mg/dL
Protein, Total,  Serum 6.8 g/dL
Albumin,  Serum 4.4 g/dL
Globulin, Total 2.4 g/dL
A/G Ratio 1.8
Bilirubin. Total 0.3 mg/dL
Alkaline Phosphatase,S 86 IU/L
AST (SGOT) 22 IU/L
ALT (SGPT) 65 IU/L

TSH 2.030 uIU/mL

Vitamin D, 25-Hydroxy 14.3 ng/mL

[TheLightSeeker]

Hey IMON22S, no need to apologize.

Some observations:
1.You doctor may not be aware of the implications of low cholesterol levels, as he may be trained to look mostly at high cholesterol (Follow the money trail-
statins are are some of the best selling drugs  in the world - there's not a single legit study which proves that their cholesterol lowering properties have
anything to do with health improvement).
2. Obesity is a factor in vitamin D resistance.
I have included a copy of a pertinent recent message to a friend, regarding vitamin d resistance:

--- Problems with Vitamin D absorption, assimilation & resistance to vit D---

--General Inflammation and G/I inflammation(very common with low thyroid or low adrenal sufferers) Leaky Gut Syndrome, Crohn's, Colitis. etc.
-- Low fat diet or issues with fat digestion also relating to not enough cholesterol for hormonal AND vitamin D synthesis ( Vit. D is fat soluble)
-- Obesity
-- Certain drugs
-- High Cortisol
-- Vitamin D Receptor (VDR) gene mutation  ( genetic /autoimmune) or decreased VDR expression, common with Hypothyroid & Hashimoto's sufferers also.
In this case need increased levels of D, above and beyond normal serum levels, for optimum function.

Also did you know that deficiency in vitamin D leads to vitamin B12 and B-complex deficiency as low vitamin D can affect the G/I system and its ability to absorb and assimilate certain nutrients and vitamins?
Also your D3 levels (vit­a­min D 25OH test) should be about 50- 60ng/ml
Memory and other neurological issues, are indirectly associated with low vitamin D, which by the way affects over 3000 genes!

Your doctor's supplementation, in light of the the above scenario, may be
inadequate.
I would suggest you consider 5000IU D3-sublingual,emulsified drops daily.
Supplementing with some vit.K2 will ensure that metabolized calcium through the vit.d gets deposited in bones, joints and teeth instead of soft tissues.
Also have your B12 and B complex levels checked, as well as thyroid.
Ask for Free T3, Free T4 and Reverse T3 to test for thyroid function.
The standard tests only indicate serum thyroid levels, which if come back normal, may keep you in perpetual limbo, since you and your doctor will know nothing about you possibly being hypothyroid.

3. Your alanine aminotransferase (ALT) is slightly above range at the time of testing, which is not predictive of disease progression or extend of liver damage at all. Normal upper range is  60 IU/L. ALT levels fluctuate, so only further testing would help assess this better.

4. A hormonal panel may return some questionable results such as cortisol levels indicated as total cortisol , which does not co-relate with bioavailable
levels of unbound cortisol, the only one that matters!
For details look into:  Functional Adrenal Stress Profile – BH #201 – Cortisol x 4, 2 averaged DHEA-S; from BioHealth Labs, FYI only as a reference.

Hope this helps.
Niko

[IMON22S]

I apologize for not including what the doctor said. He was considered about the vitamin D he told me to take 2000 IBU of vitamin D  also, he was considered about my liver. The test showed slightly high levels than normal. We are going to do another test in 4 months to recheck my vitamin D levels. Other than those two he said the basic things lose weight and eat healthy. however this is the first time my vitamin D were low, my cholesterol has always been low. I had a test done about a year ago and everything according to the doctor was normal. Also about a year and half or 2 years ago I had a hormonal panel done, I had an odd problem. I couldn't ejaculate during sex, by myself yes, but not during. The test showed nothing wrong everything was in line. He couldn't figure out what the problem was, about a year later I finally did. We just assumed it was mental. I know that past results aren't the same as current, just trying to explain a history of past results.

[TheLightSeeker]

You did not say what your doctor suggested after receiving your results.

For starters, your total cholesterol levels are very low, which may explain at least partially your dangerously low vitamin D, which affects the entire body. Vitamin D is a hormone, requiring ample cholesterol levels for its synthesis and the same goes for  the synthesis of any hormone.
A homonal panel would likely indicate mulitple hormonal deficiencies.

Almost every cell in your body has vitamin D receptors, which (vit. D) is vital for the optimum functioning of most bodily systems and organs.

Being deficient in vitamin D may affect also thyroid function, B12 levels,
and a lot more! These should all be checked!

I did not analyse  your other results, mainly because if the aforementioned
imbalances are not addresed, it would be pointless to proceed with other
investigations. simply because these are so fundamental that very much can be done, unless they are corrected first!

Oh, one more point. Your neurological function would be suffering as well
because of lower than optimum cholesterol levels, which aslo may have to do at least partially with your ADD.

Please let me know if you need more details in anything, however, I should note that my suggestions and comments are not intended to replace medical advice.

Best wishes.
Niko