I have three daughters aged 1,2 and 7. They all have hypermobile joints (fingers, wrists, elbows, knees, ankles) the youngest seems to have the most lax joints, when washing her hands you can feel the movement of joints in her wrists and fingers (she also has tethered cord syndrome). The eldest was suspected of having dyspraxia but on assessment her difficulties were put down to her hypermobility (she has no ankle reflex's, and a duplex kidney system also) She uses adapted cultery and has a pencil gripper and a sit and move cushion. All 3 have blue sclera. They had an assessment together for connective tissue disorder (query EDS). They have now been reffered to a clinical genetics clinic for further assessment.
My questions are:
What is the probability they have EDS?
If they do have this conditions will it have any long term effects on them?
What testing, if any, should I expect them to have?
Will a dx effect them if they ever have children during pregnancy? and could they pass this on in a more severe form?
Is it uncommon for 3 siblings to have these characteristics?
My brother has 2 children his eldest is fine but his baby (5months) also has blue sclera, she is to young for us to know if she will also be hypermobile. I have suspected POTS (positive tilt table test).
I thank you in advance for taking the time to respond to my post.
Kind Regards.