My basic question is: Could chronic thigh pain be attributed somehow to having the C677T mutation of the MTHFR gene? (Could there be multiple small arterial occlusions that can not be seen on a Doppler sonogram or in an MRI?)
I have had ongoing thigh pain for almost 3 years now and have not been able to obtain a diagnosis or receive any relief. The pain in the top and outside of the left thigh; Pain includes: an ongoing tired, deep dull ache; sporadic sharp, stabbing pains (stabbing down into the top or side of the thigh); occasionally the thigh muscles ache with such soreness (as one would get right after a long workout); occasionally, the entire thigh area feels as though it is slowly/softly twitching/moving/shifting.
I just stopped taking the birth control pill (after being on it for 10 years); I stopped it due to just being confirmed to have the C677T mutation of the MTHFR gene. (This was discovered after 3 of my siblings had blood clots & vision loss and were confirmed with 1 or 2 of the mutations of the MTHFR gene).
Over the last 3 years, I have had: 2 Doppler sonograms; x-rays of the leg, hip and spine; MRI of the thigh and lower back; sonogram of the aorta to rule out aneurysm; EMG and Nerve Conduction study; tried a Chiropractor for 5 months; tried orthotics inserts; and had many blood tests for: Rheumatory factors, Lymes Disease, C-Reactive protein, Lupus, homocysteine, factor V Leiden, B12, muscle enzymes, prothrombin, hemostasis, CBC, etc...Besides being confirmed to have the C677T mutation, all tests were fine.
I have tried: OTC anti-inflammatories and prescription anti-inflammatories; Physical Therapy, a pain patch, B6, B12, and the Graston Technique (in physical therapy).
I am very concerned about my strong family history of blood clots along with these MTHFR mutations and was hopeful for some insight as to if this could have anything to do with my thigh pain.
Copyright 1994-2018MedHelp.All rights reserved. MedHelp is a division of Vitals Consumer Services, LLC.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.