I'm sorry to hear that - very upsetting indeed for you both to say the least.
You are right to say that false positives may occur more frequently in pregnant women.
I would be keen that your wife has a repeat test using a different methodology and also if possible an HIV RNA PCR test. Western Blots were the gold standard but in actual fact perform poorly when compared to modern third or fourth generation HIV tests.
I have looked at the Home Access test data available on the web - and the information is not terribly full. The data it relies on seems to be from 1997 which suggests to me that it might be a second generation test - I'm not sure.
I think as I say that your wife should have a test using a modern third or fourth generation test together with an HIV RNA PCR.
I think you should have a 3rd or 4th generation test now also.
I do not believe your "exposure" was significant in any sense.
I hope some of that helps.
best regards, Sean
Thanks for your reply. Home Access uses 2nd generation testing but what I've read on the other prevention forums is that even with 2nd generation testing, it would be able to pick up any antibodies at 12 weeks. Dr H. and other mods tend to agree with that. Hope you concur but of not, please expand.
Also, should have given you an update that her WB came back indeterminate with all bands negative except p24 which was reactive. Dr. Handsfield mentioned that this is not always associated with HIV but if It was, that would likely only happen if she was exposed to in the last 1-3 weeks. Otherwise, if the exposure was 8 weeks ago (the last time we had sex), then it would be positive, with more bands reacting than just that one. If you have any opinions to add to that, I would appreciate it.
Upon your recommendation my wife and I both took an Oraquick test today. This is a third generation test, where the Home Acccess test is second generation. Both results were negative. Thank you for that advice. Would you recommend anything further? Our baby is still on HIV medication and not breastfeeding.
Thank you for your further questions. I'm sorry I'm a bit late responding but we had a power cut affecting the whole of the street in which my office is based yesterday so we were peculiarly isolated.
Good - i think thats much better news.
As I've implied - I don't like or rate second generation tests or Western Blot and I don't believe in the modern HIV testing world that they have much of a place. Certainly 2nd generations I would not bother with.
As I have said, I think your wife - and you - should have an RNA PCR test now - that will take a few days to process but will give you clarity. Because of various factors outside the scope of this Forum, testing your new infant is not helpful. The doctors attending your infant / wife have done the right thing pending the result of a definitive test.
I hope that helps you further. The fourth generation test HIV DUO includes a p24 element to it and so if you can obtain a 4th generation test for you and your wife that would assist us in this.
best regards, Sean
Upon your rec, my wife and I took PCR tests. Both came back negative. I'm under the impression that this is conclusive. Could you confirm?
Thank you for all your help.