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Avatar universal

Is a Negative test, Nega

Hello Doctors. Reading pretty much all forum I couldn't find an answer to my question. I had an negative HIV result from a exposure to CSW due to a condom breakage from 3 months ago. The test I had was a abbott architect hiv-1 and hiv-2. It was a antibody and antigen I believe(3 months after exposure). As alot of people talk about false positve results I was concerned about a false negative result.With both your experience I hope to find an answer. I will put my specific questions in point form. 1) How do testing labs cut out the false negative results?. 2)Have you heard of people who had false negative test that were within their window period and were positive.?3) From a statistical standpoint what are th numbers for a false negative with the abbott archicture? 4) I just started a course of Hep vaccination (had only 1) before my test. Could that effect my result? 5) From a assurance/ reliablity standpoint what are your thoughts? One doesn't want to feel safe and have a shock down the track of life due to a single test.
8 Responses
239123 tn?1267651214
MEDICAL PROFESSIONAL
Responding to the opening lines, I'm a little surprised you had trouble finding the answers.  We have said repeatedly that testing is always reliable 6-8 weeks (and always within 3 months) of the last possible exposure.  Always, no exceptions.  Therefore, in response to "I had an negative HIV result from a exposure to CSW due to a condom breakage from 3 months ago":  You did not catch HIV.  I don't need to read the rest of your question.

But now I have done that anyway.  To the specific questions.

1) As far as I know, labs don't do anything to exclude false negative results. They just report the results they get.

2) That has never happened in my experience.

3) Zero chance of false negative after 3 months, with any and all HIV antibody tests.  (With a dual antibody/antigen test, like you had, 100% reliability actually is reached at around 4 weeks.)

4) No medicines, illnesses, or vaccines affect HIV test reliability, with the possible excpetion of advanced chemotherapy or immunosuppressive drugs -- and even those are theoretical only, with few if any actual occurrences.

5) You don't have HIV.  You probably were not at significant risk anyway, since most CSWs don't have HIV anyway.

Time to move on.  All is well.

Regards--  HHH, MD
Avatar universal
Sorry I didn't complete that title which should say: Is a Negative test, Negative?
239123 tn?1267651214
MEDICAL PROFESSIONAL
Yup.
Avatar universal
You mentioned in your response to point  2)That has never happened in my experience. Do you relate this to your fellow doctors experience or yours and if its yours how about other doctors that specialize in the field? and comment 3) Zero chance at 3 months. Are you taking about the sensitivity instead of the specificity of the test.?  Also I have read about Elisa testing. Was the test I had an Elisa test?
As I mentioned in my last line. I want to make sure that its absolute and have no worries for the future with a test that may have been wrong. Your assurance of "Always, no exception" is nice to hear but I wanted to have 100% confidence to
move on to the future. Many thanks
239123 tn?1267651214
MEDICAL PROFESSIONAL
You need to stop splitting hairs.  The test works.  You had both an ELISA test (for HIV antibody) and a test to detect the P24 antigen of HIV.  Both components were negative.  and accept the reality that you don't have HIV -- with 100% confidence.

That's the end of this thread.  I won't have any more comments.
Avatar universal
Doctor. Please have some understanding and find it in your heart to please answer this question as it will be that last. Your answer to 3. Is that fact from the medical industry/field or from your own experience? This will let me have closure forever. Thank you with great appriciation
239123 tn?1267651214
MEDICAL PROFESSIONAL
Sigh.  Use a little common sense.  It's medical science, not just my experience.  Unless you have had more recent exposures that you don't describe, it is impossible you have HIV.

Any more anxiety driven or "did you really mean it" questions and the entire thread will be deleted without reply.  And do not be tempted to ask similar questions again in a new thread.  That would suffer the same fate, and without refund of your posting fee.
Avatar universal
Thank you. I can really move on now.
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