HIV P24\AG COMBO TEST

[nabeel161]

Dear doctor ...
good morning, first of all sorry for bad language, but i'm not native speaker.

i had oral sex with girl(she's sex worker) she kiss me deep kiss and she sucked my lips (for 2 minutes and the saliva transfered between us) after that she sucked my dick (for 3 minutes) and i ejaculated inside her mouth.all of this it was in the early morning and she told me she was with another customer before me and i saw her when she left the home for the other customer (i think she had a sex with him & they did everything). i'm so affraid if the custumer infected by HIV or the girl also.

after 4 days i saw rash on my body under armhole and on the right , also after few days i had •Diarrhea(little) + fatigue +Muscular aching(for 2 days) +•Sore throat(little).

now i did 3 tests here in United Arab Emirates (test name: HIV p24 ag - Combo Test"including hiv1 + 2 ab" ).
i did these test after 23 days & 32 days & 42 days (all of them negative).

the lab technician told me 100 % reialable and i don't need more tests and this test is 4th generation and new and they bring this machine in the previous year from roche company it's new machine.

in these days i see small lymph on my neck.

i'm so so affraid , pleaze doctor help me what can i do.

may be the symptoms Anxiety symptoms or no .

pleaze advice me.

thank you very much.

[nizar111]

A related discussion, P24 ag Combo was started.

[nabeel161]

Thank You Doctor & Sorry For Disturbance .

[Edward W Hook, MD]

This will be your last answer.  Further repetitive, anxiety driven questions will be elete without comment.

The exposure you described did not put you at risk for HIV.  Your tests for HIV are negative and are to be believed. The issue of which "generation" the test was makes no difference.  Your tests are reliable


There is also no evidence of hepatitis, syphilis, or gonorrhea.  You had blood tests performed for chlamydia which are typically not recommended because they are unreliable but they too are negative.  There is no need to repeat the tests.

Summary. There is no evidence you acquired HIV or any other STD from the encounter you described.  You need to sptop worrying.  This thread is now over.  EWH

[nabeel161]

Hi Doctor ...

Just i want to tell i did test for STDs and the results as the follwoing:

1. HIV p24 \ AG COMBO                          - NEGATIVE
2. HBs Antigen                                        - NEGATIVE
3. HCV Antibody 3rd Generation               - NEGATIVE
4. Treponema Pallidum Test(TPHA)          - NEGATIVE
5. VDRL                                                 - NEGATIVE
6.Chlamydia Antibodies(IgG)                    - NEGATIVE 0.4 EU/ml
7.Chlamydia Antibodies(IgM)                    - NEGATIVE 0.4 EU/ml
8.Special Cultures: Neisseria Gonorrhea    - Specimen: Swab, Neisseria Gonorrhea:No Growth
9. Herpeselect 2 IgG                                - NEGATIVE 7.8 u/ml

** My Dear Doctor , what is your opinion for these results and do you thing i have to repeate it again or no,

last point: i asked the doctor in the lab today and she told me the (hiv\p24 combo test) they use it in their lab 3rd generation not 4th generation so do you think there is any difference in the result or the accuracy between 3rd and 4th generation & i have to believe the result even if the combo test 3rd not 4th generation.

thank you for your help.

[Edward W Hook, MD]

This is a technical bulletin with careful wording. There are the tyical FDA required statements which related to the fact that there are, at least in theory, no perfect tests.  Practically however, as I staed, a negative test at 4 weeks is defintive evidence that you do not have HIV.   This does not change my statement.  If you choose not to believe me, that is, of course, up to you.  I am confident however of what I say.  EWH

[nabeel161]

Dear Doctor ...

What about this link:see page 27
http://www.fda.gov/downloads/BiologicsBloodVaccines/BloodBloodProducts/ApprovedProducts/LicensedProductsBLAs/BloodDonorScreening/InfectiousDisease/UCM216314.pdf

the result for this assay say the test not sure 100%

i got this link from teak (member in this forum).

pleaze help me to understand this assay (page 27)

[Edward W Hook, MD]

No risk is an opinion.  Even if there was blood in her saliva- no risk.  EWH

[nabeel161]

Sorry Doctor , but you didn't give me your opinion on this point

just i want to add last point when the girl kissed me i tasted from her saliva something like sweet ( i don't know may be this her blood and it's trnasmited to me through her saliva ).  
do you think there is any risk for that.

thank you very much and beleive me this is the last question.

i'm waiting your reply.

[Edward W Hook, MD]

1. Believe the tests.  You have seemed to missed our repeated statements that the symptoms of the ARS are TOTALLY non-specific and when people experience "ARS symptoms" they are much more likely to have something else, usually some other, more typical virus infection.  When this has been studied in the US, less than 1% of persons seeking medical care for "ARS symptoms" are found to have HIV, the remainder having symptoms due to other processes. In contrast, over a given year, there is almost no one who has not had a viral illness, night sweats or both (sometimes on multiple occasions).  In addition, it is also important to realize that many persons who acquire HIV do not experience the ARS.  For a person to try to judge their HIV risk based on "ARS symptoms" is a waste of time.

2.  This is beyond the scope of this Forum.  At 4 weeks an beyond, either anitbody or p24 antigen is present in all persons with HIV an in many peole both are present. Believe the tests.

3.  No, your exposure was NO RISK an now you have a highly reliable test which tells you that you do not have HIV. Repeating the test will not change the answer.  

EWH

[nabeel161]

Sorry Doctor, just i want to add last point when the girl kissed me i tasted from her saliva something like sweet ( i don't know may be this her blood and it's trnasmited to me through her saliva ).

[nabeel161]

Thank you doctor for your reply, but i want to ask you three questions:

Q1: you told me HIV P24 Combo test after 28 days 100% reialable, but what about symptoms i have i'm so affraid and if any person do this test any time after 28 days it's ok or no (ex. if i want to do this test after 60 days it's ok or no).

Q2: is true this test will give us good results only in the first 20 days or no, because some people said p24 antigen will dissappear after 20 days and the others said p24 antigen stay for few months, so pleaze doctor can you explain for me the procedure for this test and p24 antegin it's stay in the blood detectable for how long (the period).

Q3: do you advise me to do the test in another lab (do you think may be i got wrong result )
because i did this test three times after 23 + 32 + 42 days all of them negative, but untill this moment i have some symptoms.

Sorry for bad language.

thanks alot.

[Edward W Hook, MD]

Welcome to our Forum.  I'll try to clarify things for you.

First, you did not get HIV from the exposure you describe.  I say this for two reasons. First, none of the activates you engaged in has EVER been associated with HIV risk, not ever, in a scientifically proven manner.  That is true even if she had just had sex with another person who had HIV. Secondly, your tests are totally reliable and should be believed.  The DUO tests are entirely reliable any time more than 4 weeks after exposure.  Believe the test results.

A final point of clarification.  In reviewing the advice you received on the HIV community site, I note that you have been told that test results are not completely reliable until 3 months following exposure.  Please understand that the advice on the Community site may differ from the advice we give. The community site provides the recommendations based on information from the CDC and other official, governmental organizations.  Sometimes this information is overly conservative and out of date.  Dr. Handsfield and I provide our information based on the latest scientific information and on information we get from scientific meetings.  Thus there may sometime be a difference between the two sites.  We believe that our data is more up to date and is a reflection of having worked in the field for over 30 years each.  At the same time, we feel it is appropriate for the information provided on the community site to reflect national recommendations and guidelines.  I hope this explanation is helpful to you .  

Take care. EWH