Confusing HIV test result of my wife

[Nirav2022]

Hello Community

I am a married person for last 2.5 years. 7 months ago (29.09.2021) I had an unprotected vaginal sexual intercourse with one of my female colleague. Further, one month before we planned for a baby and went for doctor for regular checkup. She wrote some tests for my wife which included HIV 1 and 2 Antibody as well.
She gave blood on 27.03.2022 at one hospital which came out reactive and she was asked to give resample. After panic we went to other hospital for test there they did following test for her.
HIV 1 & 2 (p24 and Antibody) by Enhanced Chemiluminescence which came out rea
with 3.16 S/C value.
After that they did HIV 1 and 2 antibodies by Immunochromatography (Rapid) which came out non reactive. Further they did WB which came out Indeterminate (p24 positive). We got same indeterminate WB from the first hospital as well.

I also gave sample HIV 1and 2 by Enhanced Chemiluminescence which came out non reactive.

The female colleague with which I had sex, also went for the test last week for HIV 1and 2 antibody by ECLIA which came out negative (index 0.001) and her HIV P24 Antigen and Antibody test also came out negative.

I did HIV RNA PCR on 20.04.2022 which came out negative.

My wife did HIV Antigen and Antibody on 25.04.2022 which again came out reactive (3.41 S/C )

She is totally faithful with me and I am her only sexual partner in her life. So why her reports are like this.

Does my illicit relationship is cause of her misery.

Please help me.

[Nirav2022]

Just now her HIV-1 RNA PCR test result came and it reads "NOT DETECTED".
We live in India so we shouldn't be concerned about HIV-2.
We will try to find out why her Antibody test were reactive repeatedly.
Shall we come ot of this HIV fear now.

Thanks to all Community members and Thanks to Almighty GOD.

[CurfewX]

Yes, you can forget about HIV.  

I'm really sorry you had this troubling experience, but I'm glad your wife doesn't have HIV.  I do hope they find the cause of the false positive tests.  Take care!

[Nirav2022]

Thanks for your wishes Sir.
I have learnt a lesson for my future and will remain faithful with my wife. No words can define the suffering and guilt I felt in last one month.

We will follow up for the cause of False positive.

[DarkDJRaj]

You may not like my answer but you should go for HIV-2 RNA pcr, India has HIV-2 cases in some parts of the country .

[AnxiousNoMore]

"Your colleague tested conclusively negative, as did you.  You could not have given HIV to your wife."

[Nirav2022]

On 27.03.2021 after Indeterminate WB results, the Hospital people told us they carried out Viral Load Test in which they got nothing but they didn't gave us report and said it might be due to initial stage of infection.
One thing I want to reiterate that she is really honest and didn't have any sexual partner other than me. She didn't have any instance of any blood transfusion.
She does have some allergic conditions, and her IgE value always remain very high.

[Nirav2022]

Yes madam, she has already given the test. Report will come in day or two.

[CurfewX]

I agree with the advice given by GuitarRox.  Your colleague tested conclusively negative, as did you.  You could not have given HIV to your wife.

False positives can happen, although with multiple reactive tests, that is less likely (unless your wife has an autoimmune disease).  Has she been scheduled to take an RNA PCR test?

[Nirav2022]

Just now her HIV-1 RNA PCR test result came and it reads "NOT DETECTED".
We live in India so we shouldn't be concerned about HIV-2.
We will try to find out why her Antibody test were reactive repeatedly.
Shall we come ot of this HIV fear now.

Thanks to all Community members and Thanks to Almighty GOD.

[GuitarRox]

I'm sorry you are going through this.  YOU are negative. You did NOT give her HIV. Your partner that you had the sexual situation with also is negative. Your wife's situation is not because of you!  That's kind of hard to swallow especially since you probably have some residual guilt and this implies that your wife has a situation outside of you that she is not disclosing if she does indeed become HIV positive. So, you need to accept that. YOU are hiv negative.  The results she's gotten are inconsistent. Reactive, negative and indeterminate. That sure is confusing and is not yet enough to diagnose her as HIV positive. What is the next step for you all to get a definite answer regarding this?  That's what you need to do now.  Forget  your exposure.  You are negative as is the other person. Now you just need to help your wife.