HPV and HIV ! Late Sericonversion ?

[HPVWhy]

Hello Dr's and Everybody,

I have a question and i hope a Doctor or a Specialist can answer me.

i had on 23.06.2014 an Operation for removing
Genital Warts in a hospital in Germany, around Anus, Intraanal and Perianal. i had to do a complete STD blood also ( HIV 1+2 Ab/Ag ) test which came Negative. i must say that i had one Visible Wart since 2009 which was not good removed from a Dermatologist in another Place (Pubic Area). My Questions are:

1) Is my Negative Hiv test Conclusive after 86 days since last sex intercourse? ( Protected with a Transsexual sex worker, however i dont know if the Condom was Safe or not)

2) Are HPV or Genital warts a Symptoms of HIV? Does it effect my HIV test was taken on 86th day after Exposure?


Thanks

[Teak]

You're welcome.

[HPVWhy]

Thank you Teak !

[Teak]

Genital Warts does not have any effect on seroconversion nor would it lengthen the window period. You have conclusively tested negative. Use condoms for penetrative anal and or vaginal sex and you won't have an HIV concern.

[HPVWhy]

Thank you Teak ! what about Genital Warts and Seroconversion ?

[HPVWhy]

Teak, HowardH , Thank you for your Answers but im Confused now.
Could you please answer me without FDA,CDC etc Discussions:
1) Is my Test Conclusive ?
2) has genital warts an effect on seroconversion ?
Thx

[HowardH]

Actually, though, the CDC-FDA relationship you describe isn't accurate. FDA approval is a consideration, not the only or even the main one in developing recommendations.

[HowardH]

True. But CDC issues guidelines and recommendations on prevention of HIV (as well as STIs  and everything from malaria to influenza) that are widely considered the most reliable guidance. Few if any public health programs adhere strictly to FDA approval as the sole basis for test interpretation.

[Teak]

This is a US based website and the FDA is the governing body for HIV test and medication approvals. The CDC is a separate government entity and do not have anything to do with testing approvals.

[HowardH]

Many publically available scientific resources. And FDA approval is not the sole consideration in test interpretation and advice to patients. Some of CDC's own official treatment recommendations and test interpretation advice are in conflict with FDA approval.

[Teak]

Post where you get your information and show the FDA approvals for that.

[HowardH]

That the combo test does not detect HIV2 antigen (only antibody) is pretty much irrelevant, given how rare HIV2 infections are in the US and most industrialized countries, where almost no HIV acquired by individual sexual exposures is due to HIV2. The antibody portion of the combo test detects >95% (probably 99%) of HIV2 infections at 1 month. This, plus the rarity of HIV2, means that the negative predictive value (NPV) of a duo test at 1 month is >99.99%, which is sufficiently high to be considered 100% except in very unusual circumstances. This is the scientific basis for the confidence of virtually all US and European public health officials responsible for HIV prevention that combo testing at 1 month is conclusive.

These considerations can be different in those parts of the world where a significant minority of HIV infections are caused by HIV2, like much of Africa and parts of the Indian subcontinent.

[Teak]

Yes 12 weeks is conclusive not 28 days. The combo test can detect HIV2 any earlier than a 3rd generation test. The test does not detect antigens for HIV2. the test claim to be able to detect HIV 3 weeks earlier than a standard antibody. If an antibody test was conclusive at 12 weeks then 3 weeks earlier is 9 weeks which is 63 days not 28 days.

[HPVWhy]

Thanks. isnt 12 Weeks = 3 Months ?

[HowardH]

In fact, Eireann_guy is correct. If you want to nail it down with 100% certainty according to official recommendations from CDC, you could have an HIV antibody test at 3 months or more after the exposure. But from a scientific standpoint, your current results are conclusive.

Having genital warts and HPV is irrelevant. These are not markers of HIV risk, and have no effect on HIV test performance.

[HPVWhy]

Okay.. What is Correct ?

[Teak]

Disregard Eireann_guy replies, they are totally incorrect.

[HPVWhy]

Thanks for your Answers ! does Genital Warts has an Affect on those Tests i made or an Affect on Seroconversion ? thanks

[Eireann_guy]

Hey man,

To answer your questions (to the best of my knowledge):

1. Yes, it is conclusive. HIV DUO (or COMBO) which is Ag/Ab is conclusive from day 28 onwards, especially with regards to low risk you had (protected sex, partner with unconfirmed status). To say more, 86 days is conclusive with even antibody-only test, and you had a better one.

2. No symptoms are to be taken into consideration. The only way to know is to get tested which you did with proper test, at appropriate place and appropriate interval. Therefore, your symptoms are not HIv-related and you're HIV-negative.

[HPVWhy]

Anyone can help ?