I am a medical transcriptionist. The weekend after Thanksgiving, I reconnected with a friend of mine who works in digital audio and radio production. He was complaining of acute reduction in the hearing of his left ear, tinnitus, and headaches. He presented to an ENT, who sent him for an MRI with attention to the internal auditory canal and inner ear, which returned normal. They tried him on steroids, which did nothing to help his ear but had the side effects of weight gain and constipation. He was put on pain medicine for the headaches. A couple of days ago, he called their office again, pretty much upset and demanding results. His loss has progressed to complete loss of hearing in the left ear and partial loss of hearing in the right ear, and it's affecting his work. The nurse to whom he spoke at the ENT's office said it was likely viral and called in a prescription for Valtrex as well as a course of prednisone. He was upset about the Valtrex until I explained that herpes viruses were a family of viruses... He has also told me he does not intend to take the prednisone, as the earlier course of steroids didn't help and he didn't tolerate the side effects well. He is otherwise healthy and watches his diet, works out daily, etc. The only other symptom he has reported to me is a single episode of drenching night sweats two nights ago that left him very worried - he fell asleep and slept far longer than he normally does, and woke up soaked through in sweat. I am going to actually see him tomorrow morning and look at his ear for myself (I'm way out of practice though; I was a medical student until my own health issues forced me to leave school, so I haven't done a formal physical exam in about 14 years). Has anyone experienced sudden progressive loss of hearing like this? What kind of diagnostic questions are appropriate to ask? What kind of ideas should we be pursuing here?