Hello. I am a 33 y/o male. 6'0 193lbs. I am slightly overweight, but also carry a decent amount of muscle.
Recently I have been diagnosed with stage II diastolic dysfunction. In researching this diagnosis, I have found conflicting and/or ambiguous studies as to whether or not this condition is reversible or correctable.
The best consensus I can find is that the milder forms of the disease are reversible with exercise and possibly medication treatment. Studies also show that more restrictive stages of the disease are not reversible.
I'm struggling to get a clear answer as to how advanced my diastolic dysfunction is, and whether I can reverse it.
My ECGs are abnormal with non-specific inverted T waves, but otherwise look normal.
My Echo came back with the following findings:
Visual EF is 55-60%
Doppler evidence of grade II diastolic dysfunction
Mild mitral regurgitation
Mild mitral valve leaflet thickening
Structurally normal tricuspid valve with mild regurgitation
No evidence of pulmonary hypertension
Insignificant pericardial effusion
My MV Decel Time = 275 ms
MV Pk E Vel = .6 m/s
MV Pk A Vel = .5 m/s
MV E/A Ration 1.3
IVRT was not included in the lab report for some reason.
The left atrium was 4.0 cm, right at the edge of the normal limit. Other measurements all seem to fall into the normal ranges for my age.
When reading about the stages of diastolic dysfunction, I can't understand how I was classified as stage II. My E/A is normal, but my deceleration time is high 275, which doesn't fit either stage I or stage II.
My doctor also currently has me on 25 mg Losartan. My BP when relaxed (without meds) used to run about 138/85. When stressed, it goes up higher, and I have a stressful job. The Losartan has been doing a great job keeping my BP in check.
Studies seem to indicate abnormal relaxation is reversible, however restrictive stages of the disease are not.
I would really like to understand how progressed my disease might be, and whether or not it is reversible at this stage.
Thank you much!