Aa
Aa
A
A
A
Close
Avatar universal

mrs

after a stent inplant how long must clopidogrel-winthrop be taken my heart attack was caused by cholestral which now a 3
5 Responses
Sort by: Helpful Oldest Newest
Avatar universal
aspirin also acts directly on platelets by blocking formation of thromboxane, inhibiting aggregation.
Helpful - 0
976897 tn?1379167602
"Gotta minute to add to this?"

Sure. The easiest way to explain this is that there are two sides to the reaction for clot forming. First is the development of chemicals from the damaged cells which are sent out to attract and excite platelets into action. The second is the receptors on the platelets which sense those chemicals and start to stick together. Aspirin actually plays 2 roles. First it inhibits the release of the chemicals from the cells and second it reduces inflammation which makes artery disease progress more. Clopidogrel (Plavix) works from the side of the platelets themselves, numbing their senors which react to the chemicals from the damages cells. So you are hitting both sides of the clotting action by taking both medications. I had a lot of problems with Aspirin affecting my stomach, even the gastric resistant ones. My Cardiologist said to take just the Clopidogrel because he would choose this over aspirin anyway if one had to be chosen.
Helpful - 0
63984 tn?1385437939
I was taken off Clopidogrel after my bypass surgery because my cholesterol levels were perfect.  Soon after, my bypass veins failed totally.  I'm taking it now as well as aspirin.  Just throwing this out as something to talk to your doctor about.
Helpful - 0
Avatar universal
i was taken off clopigogrel. I still take aspirin. I'm most intrigued by your saying clop comes at the problem from another side. Gotta minute to add to this? My stent was four years ago and seems to bave been a good job.
Helpful - 0
976897 tn?1379167602
It is becoming more acceptable now that clopidogrel is a benefit for life. While aspirin works on one side of the clotting process, clopidogrel works from another. You say your heart attack was caused by cholesterol but this isn't strictly true. Cholesterol is one of the later processes which makes the heart attack happen but isn't the initial cause. The initial cause is damage to your artery linings which can be through blood pressure or bad diet. I would read up on the causes of heart disease and try to understand the different processes involved. Too many people are fighting the last stage instead of the first.
Helpful - 0
Have an Answer?

You are reading content posted in the Heart Disease Community

Top Heart Disease Answerers
159619 tn?1707018272
Salt Lake City, UT
11548417 tn?1506080564
Netherlands
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Is a low-fat diet really that heart healthy after all? James D. Nicolantonio, PharmD, urges us to reconsider decades-long dietary guidelines.
Can depression and anxiety cause heart disease? Get the facts in this Missouri Medicine report.
Fish oil, folic acid, vitamin C. Find out if these supplements are heart-healthy or overhyped.
Learn what happens before, during and after a heart attack occurs.
What are the pros and cons of taking fish oil for heart health? Find out in this article from Missouri Medicine.
How to lower your heart attack risk.