Sorry to hear about your symptoms. There are options for people with severe symptoms from PVCs that do not improved with beta blockers: medical therapy with medications like flecainide or ablation.
Ablation is an option for people with PVCs of the same shape (morphology) on 12 lead EKG, preferably coming from the right ventricular outflow tract location. The RV outflow tract is an easier to ablate compared to other locations. If there are multiple morphologies, the ablation is more difficult and is less likely to be succesful.
Medications like flecainide can suppress PVCs. It is a good option for people with structurally normal hearts and no coronary artery disease. There is an increased incidence of dangerous arrhythmias in people with coronary artery disease. Peope with reduced heart function or conduction system disease can have progression of their dysfunction on medications like flecainide. Rhythmol, Sotalol and Tikosyn are other options, but most prefer to use flecainide. The use of flecainide also requires that a beta blocker be given. If you develop an arrhythmia like atrial flutter, flecainide can cause the rhythm to conduct very quickly, beta blockers are used to decrease this risk. Flecainide is a good option for the appropriate patient -- it sounds like you might qualify.
I hope this anwers your questions. Thanks for posting.
I know what you are going through, I have PCV's really bad at night, I also have them every other beat and it really puts a spin on my sleeping. I wake up having night terrors a lot because I go to bed thinking about it. I usually sleep at my boyfriends if its really bad, having someone there eases my mind a bit.