Heart Rhythm Community
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12182312 tn?1427687556

Question about Medications

Hi everyone. Quick question
And I still will ask my doctor about this, but wanted your opinion. I take Paxil for depression, well generic brand, and also metoprolol for fast palpitations. My paroxetine is 40mg, and metoprolol is 25mg. Are they safe to take together. Is one an upper, one a downer. I take Paxil in the morning, metoprolol before bed.
Thank you
2 Responses
1423357 tn?1511089042
Yes, ask your physician.  But I believe it is safe to take these two drugs together.  SSRIs like paroxetine are a type of antidepressant that works by increasing the amount of serotonin in the brain, while metoprolol is a beta blocker which works on the heart. What type of metoprolol are you taking.  Metoprolol Tartrate or Metoprolol Succinate?
Hi Tom I am on Metoprolol Succ Er
1530171 tn?1448133193
There's a moderate interaction between those 2 drugs.

From the drug interaction checker:

"Using metoprolol together with PARoxetine may increase the effects of metoprolol. Contact your doctor if you experience uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions). If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.".

I hope it helps,
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