I had an ablation two weeks ago for SVT and AVNRT. Previous to the ablation I was taking 50 mg of atenolol daily. My doctor advised me to discontinue the atenolol for 4 days prior to the ablation, and take 1/2 dose for 4 days prior to that. I was told that the atenolol may inhibit the abilities of the doc to stimulate my heart which would make it difficult to determine where the exact problem was. I don't know if it would be different for WPW but that was my experience.
Hope the ablation is successful for your wife.
Good luck with the Ablation. I understand the procedure is very effective in treating WPW.
Call your doctors office, you should be able to get an answer without going into see the doctor, what has to be stopped has to be a regular procedure for them, the front office must know, or can check with the surgeon/specialist.
In general, aspirin and anything that "thins" the blood is stopped several days before any procedure that may cause bleeding. I'm not saying this is the case for Ablation, I don't know, but I do know you need to check.
Again, keep a positive attitude, I read a lot of good things about Ablation for the subject condition.